SML0807

PreQ1 dihydrochloride

≥98% (HPLC), PreQ1 riboswitch regulator, powder

• 別名: 2-Amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride, 7-Aminomethyl-7-deazaguanine dihydrochloride, Pre-queuosine1 dihydrochloride
• 実験式（ヒル表記法）: C₇H₉N₅O · 2HCl
• CAS番号: 86694-45-3
• 分子量: 252.10
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

特性

• 製品名: PreQ1 dihydrochloride, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to light brown
• solubility: DMSO: 5 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: Cl.Cl.[nH]1c2nc([nH][c](c2c(c1)CN)=O)N
• InChI key: WUMBRQKOLVTYTB-UHFFFAOYSA-N

詳細

Biochem/physiol Actions

PreQ1 (pre-queuosine1) is an intermediate of the queuosine pathway. Also, PreQ1 binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression.

PreQ1 (pre-queuosine1), an intermediate of the queuosine pathway, regulates the PreQ1 riboswitch.

PreQ1 is a nucleobase derived from guanine and a precursor of the modified base queuosine that is present in four tRNAs. Prequeuosine (preQ1) riboswitches are RNA regulatory elements present in the 5′ UTR of genes that participates in the biosynthesis and transport of preQ1.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

安全性情報

• ピクトグラム: GHS07
• 注意喚起語: Warning
• ハザードコード: H302,H315,H319,H335
• 注意事項: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標的臓器: Respiratory system
• 保管分類: 11 - Combustible Solids
• WGK: WGK 3
• 引火点 (F): Not applicable
• 引火点（°C）: Not applicable