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Merck

GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1

Synonimy:
GluN1, MRD8, NMDA1, NMDAR1, NR1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Spermine tetrahydrochloride, powder or crystals,
Gatunek
human
D-Serine, ≥98% (TLC),
Gatunek
human
Taurine, ≥99%,
Gatunek
human, rat
D-Cycloserine, synthetic,
Gatunek
human
Dextromethorphan hydrobromide monohydrate, ≥99% (TLC),
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
S-(+)-Ketamine hydrochloride, ,
Gatunek
human
(±)-Ketamine hydrochloride, solid,
Gatunek
human
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
CP-101,606, ≥98% (HPLC),
Gatunek
human
MDL 105,519, ≥98% (HPLC), solid,
Gatunek
rat, human
Dextrorphan tartrate, powder,
Gatunek
human
Arcaine sulfate salt, ,
Gatunek
human
Ifenprodil (+)-tartrate salt, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-fosfo-GRIN1-S890produkowane u królików, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Monoklonalny anty-Glun1-Nr1- Percp, clone S308-48, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Monoklonalny anty-Glun1-Nr1- Rpe, clone S308-48, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Monoklonalny anty-Glun1-Nr1- Atto 594, clone S308-48, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Anty-NMDAR1, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Gatunek
human
Agmatine sulfate salt, ≥97%, powder,
Gatunek
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Taurine, ≥99%,
Gatunek
human, rat
Pentamidine isethionate salt, powder,
Gatunek
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human GRIN1,
Gatunek
human
MISSION® esiRNA, targeting mouse Grin1,
Gatunek
mouse