O100

Oxotremorine M

muscarinic acetylcholine receptor agonist, solid

• Synonim(y): N,N,N,-Trimethyl-4-(2-oxo-1-pyrrolidinyl)-2-butyn-1-ammonium iodide, Oxotremorine methiodide
• Wzór empiryczny (zapis Hilla): C₁₁H₁₉IN₂O
• Numer CAS: 63939-65-1
• Masa cząsteczkowa: 322.19
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277861
• NACRES: NA.77
• MDL number: MFCD00055133
• Form: solid

Właściwości

• Nazwa produktu: Oxotremorine M, solid
• form: solid
• Quality Segment: 200
• color: white
• solubility: H₂O: 24 mg/mL, ethanol: 4.6 mg/mL
• storage temp.: 2-8°C
• SMILES string: [I-].C[N+](C)(C)CC#CCN1CCCC1=O
• InChI: 1S/C11H19N2O.HI/c1-13(2,3)10-5-4-8-12-9-6-7-11(12)14;/h6-10H2,1-3H3;1H/q+1;/p-1
• InChI key: VVLMSCJCXMBGDI-UHFFFAOYSA-M
• Gene Information: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Opis

Application

Oxotremorine M has been used as a muscarinic acetylcholine receptor (mAchR) agonist:

• to study its acute effects on the movement of Caenorhabditis elegans
• to treat hippocampal neurons for studying fibroblast growth factor receptor 1 (FGFR1) phosphorylation
• to induce bladder overactivity in rats

Biochem/physiol Actions

Oxotremorine M is a nonselective muscarinic acetylcholine receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) and Acetylcholine Receptors (Nicotinic) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06
• Słowo ostrzegawcze: Danger
• Kody zagrożeń: H300 + H310 + H330
• Ostrzeżenia: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• PPE (środki ochrony indywidualnej): Eyeshields, Gloves, type N95 (US)