MX1123

1-Methylimidazole

• Synonym(s): 1-Methylimidazole, N-Methylimidazole, dna
• Linear Formula: CH₃-NCH=NCH=CH-
• CAS Number: 616-47-7
• UNSPSC Code: 12352100
• EC Index Number: 210-484-7
• MDL number: MFCD00005292
• Form: liquid

Properties

• vapor pressure: 0.4 hPa ( 20 °C)
• Quality Segment: 200
• form: liquid
• pH: 9.5-10.5 (20 °C, 50 g/L in H₂O)
• bp: 198 °C/1013 hPa
• mp: -2 °C
• transition temp: flash point 92 °C
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [n]1(cncc1)C
• InChI: 1S/C4H6N2/c1-6-3-2-5-4-6/h2-4H,1H3
• InChI key: MCTWTZJPVLRJOU-UHFFFAOYSA-N

Description

Application

1-Methylimidazole can be used as an organocatalyst to synthesize:

• 4-amino-3,5-dicyano-6-arylphthalates via one-pot, a three-component reaction between arylidenemalononitriles, dialkyl ­acetylenedicarboxylates, and malononitrile.
• Aromatic and aliphatic carbamates from hydroxamic acids via the Lossen rearrangement.
• Tetrahydrobenzo[b]pyrans via three-component cyclocondensation reaction between aromatic aldehydes, malononitrile, and dimedone.

It can also be used as:

• A co-catalyst in copper-catalyzed, greener oxidation of alcohols to carbonyl compounds under aerobic conditions.
• A solvent/complexing agent in the preparation of CuInS₂ n-type semiconductive particles.
• A co-additive in the synthesis of acid-sensitive epoxides by methyltrioxorhenium-catalyzed epoxidation of alkenes with H₂O₂.

Analysis Note

Assay (GC)99.0% minDensity at 20°C1.03-1.04g/mLFormClear, liquidWater (H2O)150ppm max

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Codes: H302,H311,H314,H361d
• Precautionary Statements: P202 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Flash Point (°F): 197.6 °F - closed cup
• Flash Point (°C): 92 °C - closed cup