04076

6-(p-Toluidino)-2-naphthalenesulfonyl chloride

suitable for fluorescence, ≥98.0% (HPLC)

• Synonym(s): 2,6-TNS-Cl, 6-(4-Methylanilino)naphthalene-2-sulfonylchloride, 6-[(4-methylphenyl)amino]-2-naphthalenesulfonylchloride
• Empirical Formula (Hill Notation): C₁₇H₁₄ClNO₂S
• CAS Number: 62778-24-9
• Molecular Weight: 331.82
• NACRES: NA.32
• PubChem Substance ID: 329747873
• UNSPSC Code: 12352116
• MDL number: MFCD00037749
• Beilstein/REAXYS Number: 6521872

Properties

• Quality Segment: 100
• assay: ≥98.0% (HPLC)
• solubility: DMF: soluble, acetonitrile: soluble
• fluorescence: λ_ex 381 nm in methanol
• suitability: suitable for fluorescence
• storage temp.: 2-8°C
• SMILES string: Cc1ccc(Nc2ccc3cc(ccc3c2)S(Cl)(=O)=O)cc1
• InChI: 1S/C17H14ClNO2S/c1-12-2-6-15(7-3-12)19-16-8-4-14-11-17(22(18,20)21)9-5-13(14)10-16/h2-11,19H,1H3
• InChI key: NONZPGMJWHNDKP-UHFFFAOYSA-N

Description

Application

6-(p-Toluidino)-2-naphthalenesulfonyl chloride is a fluorescent, hydrophobic probe utilized for labeling peptides to monitor conformational changes of a molecular assembly by measuring alterations in fluorescence intensity .

Analysis Note

Em_max: none
do not dissolve in DMSO

Other Notes

Probe for determining the polarity in biological matrices

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves