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A0835

N-Acetyl-Asp-Glu-Val-Asp-al

≥95%, powder

Synonym(s):

Ac-DEVD-CHO

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Size/SKUAvailabilityPrice
1 mg

Available to ship TODAYfromMILWAUKEE

$178.00
$151.30
5 mg

Estimated to ship onOctober 20, 2026

$613.00

About This Item

Empirical Formula (Hill Notation):
C20H30N4O11
CAS Number:
169332-60-9
Molecular Weight:
502.47
NACRES:
NA.32
PubChem Substance ID:
24890193
UNSPSC Code:
12352209
MDL number:
MFCD00671412

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biological source

synthetic

Quality Segment

assay

≥95%

form

powder

color

white

solubility

H2O: 1 mg/mL

storage temp.

−20°C

SMILES string

[H]C(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(C)=O)C(C)C

InChI

1S/C20H30N4O11/c1-9(2)17(20(35)22-11(8-25)6-15(29)30)24-18(33)12(4-5-14(27)28)23-19(34)13(7-16(31)32)21-10(3)26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)(H,22,35)(H,23,34)(H,24,33)(H,27,28)(H,29,30)(H,31,32)

InChI key

UMBVAPCONCILTL-UHFFFAOYSA-N

Gene Information

General description

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) is a tetrapeptide with N-terminal acetylation and C-terminal aldehyde conjugation.

Application

N-Acetyl-Asp-Glu-Val-Asp-al has been used as a caspase inhibitor in muscle samples, smooth muscle cells and Jurkat T-cells.

Biochem/physiol Actions

N-Acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO) aids in the recovery of stunned myocardium by its caspase inhibition functionality.
Reversible inhibitor of IL-1β converting enzyme (ICE); inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).

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This Item
235420A6339A2559
N-Acetyl-Asp-Glu-Val-Asp-al ≥95%, powder

Sigma-Aldrich

A0835

N-Acetyl-Asp-Glu-Val-Asp-al

Caspase-3 Inhibitor I The Caspase-3 Inhibitor I, also referenced under CAS 169332-60-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.

Sigma-Aldrich

235420

Caspase-3 Inhibitor I

N-Acetyl-Val-Glu-Ile-Asp-al ~99% (HPLC), powder

Sigma-Aldrich

A6339

N-Acetyl-Val-Glu-Ile-Asp-al

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide ≥97% (HPLC), powder

Sigma-Aldrich

A2559

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide

description

≥95%, powder

description

The Caspase-3 Inhibitor I, also referenced under CAS 169332-60-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.

description

~99% (HPLC), powder

description

≥97% (HPLC), powder

biological source

synthetic

biological source

-

biological source

-

biological source

-

assay

≥95%

assay

≥90% (HPLC)

assay

~99% (HPLC)

assay

≥97% (HPLC)

Gene Information

human ... CASP1(834), CASP3(836), CASP7(840), CASP8(841)

Gene Information

-

Gene Information

human ... CASP6(839)

Gene Information

human ... CASP3(836)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

form

powder

form

solid

form

powder

form

powder

solubility

H2O: 1 mg/mL

solubility

DMSO: 5 mg/mL, water: soluble

solubility

H2O: 1 mg/mL

solubility

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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