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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $169.00 |
About This Item
Empirical Formula (Hill Notation):
C21H25N3 · 2HCl · xH2O
CAS Number:
Molecular Weight:
392.37 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
eCl@ss:
32160701
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
H2O: ≥10 mg/mL
storage temp.
2-8°C
SMILES string
O.Cl.Cl.CN1CCc2c(C1)c3cc(C)ccc3n2CCc4ccc(C)nc4
InChI
1S/C21H25N3.2ClH.H2O/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17;;;/h4-7,12-13H,8-11,14H2,1-3H3;2*1H;1H2
InChI key
QQHQMWVYYVVAOV-UHFFFAOYSA-N
Biochem/physiol Actions
Mechanism of neuroprotection and cognition enhancement is not certain, but Dimebon blocks both cholinesterase and the NMDA receptor simultaneously and also appears to block the action of neurotoxic β-amyloid proteins and inhibit L-type calcium channels, and may exert a neuroprotective effect by blocking a novel target that involves mitochondrial pores.
Features and Benefits
This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | ||
|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC), solid | description >98% (HPLC), lyophilized powder |
| form powder | form solid | form lyophilized powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay >98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 200 |
| storage temp. 2-8°C | storage temp. - | storage temp. −20°C |
| solubility H2O: ≥10 mg/mL | solubility DMSO: 15 mg/mL | solubility - |
| color white to off-white | color off-white | color - |
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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