N4875

Naphthol AS-MX phosphate

phosphatase substrate, fluorogenic, ≥99% (HPLC), powder

• Synonym(s): 3-Hydroxy-2-naphtho-2′,4′-xylidide Phosphate, N-(2,4-Dimethylphenyl)-3-(phosphonooxy)-2-naphthalenecarboxamide
• Empirical Formula (Hill Notation): C₁₉H₁₈NO₅P
• CAS Number: 1596-56-1
• Molecular Weight: 371.32
• NACRES: NA.83
• PubChem Substance ID: 24897714
• UNSPSC Code: 12352204
• EC Number: 216-480-1
• MDL number: MFCD00042711
• Beilstein/REAXYS Number: 6664873

Properties

• Product Name: Naphthol AS-MX phosphate, powder, ≥99% (HPLC)
• Quality Segment: 200
• assay: ≥99% (HPLC)
• form: powder
• technique(s): protein detection: suitable
• solubility: ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow (to Faint Brown)
• storage temp.: −20°C
• SMILES string: Cc1ccc(NC(=O)c2cc3ccccc3cc2OP(O)(O)=O)c(C)c1
• InChI: 1S/C19H18NO5P/c1-12-7-8-17(13(2)9-12)20-19(21)16-10-14-5-3-4-6-15(14)11-18(16)25-26(22,23)24/h3-11H,1-2H3,(H,20,21)(H2,22,23,24)
• InChI key: IOMLBTHPCVDRHM-UHFFFAOYSA-N

Description

General description

Naphthol AS-MX phosphate is soluble in dioxane and is a substrate for phosphatase.

Application

Naphthol AS-MX phosphate has been used as:

• a substrate for alkaline phosphatase in human osteoblasts
• mouse embryonic stem cell (mESC)
• coronal plane sections for fluorescence staining and analysis

Substrate for the histochemical demonstration of alkaline phosphatase.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves