MAB377A5

抗-NeuN抗体，克隆A60，Alexa Fluor^™ 555结合物

Name: 抗-NeuN抗体，克隆A60，Alexa Fluor<SUP>™</SUP> 555结合物
Brand: MM

clone A60, from mouse, ALEXA FLUOR^™ 555

同義詞:

NEUronal Nuclei, Neuronal Nuclei

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分類程式碼代碼:

12352203

eCl@ss:

32160702

NACRES:

NA.41

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生物源

mouse

品質等級

100

共軛

ALEXA FLUOR^™ 555

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

A60, monoclonal

物種活性

rat, mouse

技術

immunocytochemistry: suitable
immunohistochemistry: suitable

同型

IgG1

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Rbfox3(52897)
rat ... Rbfox3(287847)

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本產品	MAB377C3	ABN78A4	ABN78C3
Sigma-Aldrich MAB377A5 抗-NeuN抗体，克隆A60，Alexa Fluor^™ 555结合物	Sigma-Aldrich MAB377C3 Anti-NeuN Antibody, clone A60, Cy3 Conjugate	Sigma-Aldrich ABN78A4 抗NeuN（兔）抗体，Alexa Fluor^™488偶联物	Sigma-Aldrich ABN78C3 Anti-NeuN (rabbit) Antibody, Cy3 Conjugate
species reactivity rat, mouse	species reactivity rat	species reactivity rat, mouse	species reactivity rat, mouse
clone A60, monoclonal	clone A60, monoclonal	clone polyclonal	clone polyclonal
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate ALEXA FLUOR^™ 555	conjugate CY3 conjugate	conjugate ALEXA FLUOR^™ 488	conjugate CY3 conjugate
Gene Information mouse ... Rbfox3(52897) rat ... Rbfox3(287847)	Gene Information mouse ... Rbfox3(52897) rat ... Rbfox3(287847)	Gene Information mouse ... Rbfox3(52897) rat ... Rbfox3(287847)	Gene Information mouse ... Rbfox3(52897) rat ... Rbfox3(287847)
biological source mouse	biological source mouse	biological source rabbit	biological source rabbit

一般說明

NeuN抗体（神经元核；克隆A60）特异性识别DNA结合的神经元特异性蛋白NeuN，该蛋白存在于所有检验的脊椎动物的大多数CNS和PNS神经元细胞类型中。NeuN蛋白的分布明显局限于胎儿和成人大脑中的神经元细胞核、核周体和一些近端神经元突起，但有些神经元在所有年龄段都不能被NeuN识别：例如，INL视网膜细胞、Cajal Retzius细胞、Purkinje细胞、下橄榄核和齿状核神经元以及交感神经节细胞（Mullen等人，1992；Wolf等人，1996）。免疫组织化学可检测到的NeuN蛋白首先出现在与神经元退出细胞周期和/或神经元终末分化开始相对应的发育时间点（Mullen等人，1992）。免疫反应性出现在小鼠神经管中的E9.5附近，并在E12.5的整个发育中的神经系统中广泛存在。强烈的核染色表明核调节蛋白功能。但是，目前尚无关于NeuN蛋白抗原是否在远端细胞质中具有功能或在转运回细胞核之前仅在那里合成的证据。从纯化的细胞核和全脑提取物中分离的蛋白质在免疫印迹上没有发现差异（Mullen等人，1992）。

未偶联的亲本抗体（目录号MAB377）的分子量在46-48 kDa范围内，可能在约66 kDa处有另一条条带

應用

免疫组织化学分析：一个代表性批次以1:100稀释度在成年小鼠脑冷冻切片中检测到NeuN。

该抗NeuN抗体（克隆A60，Alexa Fluor 555结合物）经验证可用于ICC、IHC检测NeuN。

分析報告

通过免疫细胞化学在大鼠E18原代皮层细胞中进行评估。

免疫细胞化学分析：该抗体以1:100稀释度在大鼠E18原代皮层细胞中检测到NeuN。

其他說明

已证明未结合的抗NeuN抗体可用于多种物种，包括人、雪貂、鸡和禽类。

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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抗-NeuN抗体，克隆A60，Alexa Fluor™ 555结合物

clone A60, from mouse, ALEXA FLUOR™ 555