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8.52002

Sigma-Aldrich

Fmoc-Met-OH

Novabiochem®

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Synonym(s):
Fmoc-Met-OH, N-α-Fmoc-L-methionine
Empirical Formula (Hill Notation):
C20H21NO4S
CAS Number:
Molecular Weight:
371.45
MDL number:
EC Index Number:
276-258-5

Quality Level

product line

Novabiochem®

assay

≥98% (TLC)
≥98.0% (acidimetric)
≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

130-140 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-30°C

InChI

1S/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)

InChI key

BUBGAUHBELNDEW-UHFFFAOYSA-N

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vibrant-m

8.52002

Fmoc-Met-OH

vibrant-m

8.52054

Fmoc-Met(O)-OH

vibrant-m

8.52212

Fmoc-Met(O₂)-OH

vibrant-m

8.52225

Fmoc-Met-OPfp

form

powder

form

powder

form

powder

form

powder

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

assay

≥98% (TLC), ≥99.0% (HPLC), ≥98.0% (acidimetric)

assay

≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

assay

≥90.0% (acidimetric), ≥97.0% (HPLC), ≥98% (TLC)

assay

≥97.0% (HPLC)

mp

130-140 °C

mp

-

mp

-

mp

130-140 °C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

15-25°C

General description

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of methionine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1003

Analysis Note

Color (visual): white to off white
Appearance of substance (visual): powder
Color index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Met-OH (HPLC): ≤ 0.2 % (a/a)
Fmoc-Met-Met-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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