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E9502

Sigma-Aldrich

EPPS

≥99.5% (titration)

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Synonym(s):
4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid, 4-(2-Hydroxyethyl)piperazine-1-propanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(3-propanesulfonic acid), HEPPS
Empirical Formula (Hill Notation):
C9H20N2O4S
CAS Number:
Molecular Weight:
252.33
Beilstein:
3957385
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99.5% (titration)

form

powder

pH

7.3-8.7

useful pH range

7.3-8.7

pKa (25 °C)

8.0

pKa 

8

mp

237-239 °C (lit.)

solubility

H2O: 25 g + 50 mL, clear, colorless

λmax

A290 at ≤0.1 (C=33% w/w)

application(s)

diagnostic assay manufacturing

SMILES string

OCCN1CCN(CCCS(O)(=O)=O)CC1

InChI

1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)

InChI key

OWXMKDGYPWMGEB-UHFFFAOYSA-N

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This Item
E1894E0276H7637
EPPS ≥99.5% (titration)

Sigma-Aldrich

E9502

EPPS

-
EPPS BioXtra, ≥99.5% (titration)

Sigma-Aldrich

E1894

EPPS

Premium Grade
EPPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

Sigma-Aldrich

E0276

EPPS

Premium Grade
HEPES hemisodium salt ≥99% (titration)

Sigma-Aldrich

H7637

HEPES hemisodium salt

-
form

powder

form

powder

form

crystalline powder

form

powder

pH

7.3-8.7

pH

5.0-7.0 (20 °C, 1 M in H2O)

pH

7.3-8.7

pH

7.4-7.7 (25 °C, 0.1 M in water)

mp

237-239 °C (lit.)

mp

237-239 °C (lit.)

mp

237-239 °C (lit.)

mp

-

solubility

H2O: 25 g + 50 mL, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

H2O: 25 g + 50 mL, clear, colorless

solubility

water: soluble 0.5 g/mL

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

Application

EPPS has been used:
  • to verify the effect of pH variation on the proteolytic activity of the posterior midgut (PMG) contents and anterior midgut (AMG) tissue homogenate
  • to prepare a destaining buffer to destain intensely stained gel pieces
  • to prepare digestion buffer for in-gel enzymatic digestion
  • to reconstitute the digested peptides for the processing of brain-derived extracellular vesicle (EV) proteins and 16-plex isobaric tandem mass tag (TMT) peptide labeling

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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