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  • A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress.

A Benzylideneacetophenone Derivative Induces Apoptosis of Radiation-Resistant Human Breast Cancer Cells via Oxidative Stress.

Biomolecules & therapeutics (2017-05-31)
Jeong Eon Park, Mei Jing Piao, Kyoung Ah Kang, Kristina Shilnikova, Yu Jae Hyun, Sei Kwan Oh, Yong Joo Jeong, Sungwook Chae, Jin Won Hyun
PMID28554201
ABSTRACT

Benzylideneacetophenone derivative (1E)-1-(4-hydroxy-3-methoxyphenyl) hept-1-en-3-one (JC3) elicited cytotoxic effects on MDA-MB 231 human breast cancer cells-radiation resistant cells (MDA-MB 231-RR), in a dose-dependent manner, with an IC

MATERIALS
Product Number
Brand
Product Description
S5567
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SP600125, ≥98% (HPLC)
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T4069
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JC-1, powder or solid (Crystals)
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559389
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SB 203580, SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC50 = 34 nM in vitro, 600 nM in cells).
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D6883
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2′,7′-Dichlorodihydrofluorescein diacetate, ≥97%
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262048
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1,3-Bis(diphenylphosphino)propane, 97%
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A2835
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Amyloid Protein Non-Aβ Component, ≥80% (HPLC)
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662005
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