577944

Hoveyda-Grubbs Catalyst^® M700

solid, Umicore

• Synonym(s): Hoveyda-Grubbs Catalyst^® 1st Generation, Hoveyda-Grubbs Catalyst^® M70 (C601), Dichloro(2-isopropoxyphenylmethylene) (tricyclohexylphosphine)ruthenium(II), Dichloro(o-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium(II)
• Empirical Formula (Hill Notation): C₂₈H₄₅Cl₂OPRu
• CAS Number: 203714-71-0
• Molecular Weight: 600.61
• UNSPSC Code: 12161600
• PubChem Substance ID: 24880901
• NACRES: NA.22
• MDL number: MFCD03453042
• eCl@ss: 32150319

Properties

• Product Name: Hoveyda-Grubbs Catalyst^® M700, Umicore
• Quality Segment: 100
• product line: Grubbs Catalyst^® M700 Series
• form: solid
• reaction suitability: core: ruthenium, reaction type: Olefin Metathesis, reagent type: catalyst; reaction type: Ring Opening Metathesis Polymerisation
• manufacturer/tradename: Umicore Grubbs Catalyst^® M700 Series
• greener alternative product characteristics: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Sustainability features
• mp: 195-197 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: [H]\C(c1ccccc1OC(C)C)=[Ru](\Cl)Cl.C2CCC(CC2)P(C3CCCCC3)C4CCCCC4
• InChI: 1S/C18H33P.C10H12O.2ClH.Ru/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;1-8(2)11-10-7-5-4-6-9(10)3;;;/h16-18H,1-15H2;3-8H,1-2H3;2*1H;/q;;;;+2/p-2
• InChI key: KMKCJXPECJFQPQ-UHFFFAOYSA-L

Description

General description

Aligned with Green Chemistry principle, ′Catalysis,′ this product is a next-generation Hoveyda-Grubbs catalyst with enhanced stability and activity. It enables challenging metathesis reactions with improved functional group tolerance and recyclability. Click here for more information.

Application

Proven to be useful in Ring-Closing Metathesis (RCM) to form macrocycles. Also employed in a pivotal, macrocyclic ring-closing metathesis in the multi-step synthesis of an HCV protease inhibitor.

Learn more about our metathesis catalysts

Other Notes

Grubbs Catalyst^® Technology for Olefin Metathesis by Aldrich

Legal Information

Product of Umicore

Additional information available at http://www.pmc.umicore.com

Grubbs Catalyst is a registered trademark of Umicore AG & Co. KG

Safety Information

• Pictograms: GHS02
• Signal Word: Warning
• Hazard Codes: H228
• Precautionary Statements: P210 - P240 - P241 - P280 - P370 + P378
• Hazard Classifications: Flam. Sol. 2
• Storage Class: 4.1B - Flammable solid hazardous materials
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)