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G4875

D-(+)-Glucosamine hydrochloride

≥99% (HPLC), powder

Synonym(s):

2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H13NO5 · HCl
CAS Number:
66-84-2
Molecular Weight:
215.63
PubChem Substance ID:
24895187
UNSPSC Code:
12352201
MDL number:
MFCD00135831
NACRES:
NA.25
EC Number:
200-638-1
Beilstein/REAXYS Number:
4157370

Key Documents

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Product Name

D-(+)-Glucosamine hydrochloride, ≥99% (HPLC), powder

InChI key

QKPLRMLTKYXDST-NSEZLWDYSA-N

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1

SMILES string

Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

biological source

Aspergillus niger

assay

≥99% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

white

mp

190-194 °C (dec.) (lit.)

solubility

water: 100 mg/mL, clear, colorless

storage temp.

room temp

Quality Level

200

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1 of 4

This Item
PHR1199Y0001381346299
D-(+)-Glucosamine hydrochloride ≥99% (HPLC), powder

Sigma-Aldrich

G4875

D-(+)-Glucosamine hydrochloride

Glucosamine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1199

Glucosamine hydrochloride

Glucosamine for system suitability European Pharmacopoeia (EP) Reference Standard

Y0001381

Glucosamine for system suitability

D(+)Glucosamine, Hydrochloride

Millipore

346299

D(+)Glucosamine, Hydrochloride

assay

≥99% (HPLC)

assay

-

assay

-

assay

≥99% (by Assay)

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

biological source

Aspergillus niger

biological source

-

biological source

-

biological source

-

solubility

water: 100 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

water: 5 mg/mL

Quality Level

200

Quality Level

300

Quality Level

-

Quality Level

100

form

powder

form

-

form

-

form

solid

Application

D-(+)-Glucosamine hydrochloride has been used:
  • as a standard to quantify and express chitin content as glucosamine equivalents.[1]
  • to stimulate cells with glucose in the presence of glucosamine[2]

Biochem/physiol Actions

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6635
BCCN6634
BCCN3860
BCCN3859
0000432701

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Luana C Farnesi et al.
PloS one, 7(1), e30363-e30363 (2012-02-01)
Population control of the dengue vector mosquito, Aedes aegypti, is difficult due to many reasons, one being the development of resistance to neurotoxic insecticides employed. The biosynthesis of chitin, a major constituent of insect cuticle, is a novel target for
Nagissa Mahmoudi et al.
Environmental microbiology, 22(5), 1734-1747 (2019-11-25)
Marine microorganisms play a fundamental role in the global carbon cycle by mediating the sequestration of organic matter in ocean waters and sediments. A better understanding of how biological factors, such as microbial community composition, influence the lability and fate
Yang Ge et al.
PloS one, 14(4), e0215834-e0215834 (2019-04-24)
Pear psylla, Cacopsylla chinensis (Yang & Li) are present as two seasonal morphotypes in pear orchards where they, suck phloem sap, defoliate pear trees, and cause fruit russet. Despite the importance of natural enemies in psyllid control, the interactions between
Chao Yang et al.
The Plant cell, 31(1), 172-188 (2019-01-06)
To defend against pathogens, plants have developed complex immune systems, including plasma membrane receptors that recognize pathogen-associated molecular patterns, such as chitin from fungal cell walls, and mount a defense response. Here, we identify a chitinase, MoChia1 (Magnaporthe oryzae chitinase
Neptun Yousefi et al.
Carbohydrate polymers, 253, 117273-117273 (2020-12-07)
Membranes and filters are essential devices, both in the laboratory for separation of media, solvent recovery, organic solvent and water filtration purposes, and in industrial scale applications, such as the removal of industrial pollutants, e.g. heavy metal ions, from water.
View All Related Papers

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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