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O5889

Opipramol dihydrochloride

≥98% (HPLC), solid

Synonym(s):

4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol dihydrochloride

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Size/SKUAvailabilityPrice
25 mg
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$135.00
100 mg
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$421.00

About This Item

Empirical Formula (Hill Notation):
C23H29N3O · 2HCl
CAS Number:
Molecular Weight:
436.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
213-000-2
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated

$135.00


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Quality Segment

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

yellow

solubility

H2O: ~24 mg/mL

SMILES string

Cl[H].Cl[H].OCCN1CCN(CCCN2c3ccccc3C=Cc4ccccc24)CC1

InChI

1S/C23H29N3O.2ClH/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26;;/h1-4,6-11,27H,5,12-19H2;2*1H

InChI key

DLTOEESOSYKJBK-UHFFFAOYSA-N

General description

Opipramol acts as an antidepressant and is chemically similar to tricyclic antidepressants. It is an atypical anxiolytic and antidepressant drug. Opipramol mainly acts on sigma receptors. It is usually found to be much effective in depressive disorder. It has the ability to prevent histamine, serotonin, dopamine and alpha-1 adrenergic receptors.

Biochem/physiol Actions

σ1/σ2 opioid receptor agonist; an antagonist at D2, 5HT2 and H1 receptors; atypical antidepressant, antipsychotic and anxiolytic
Atypical antidepressant, antipsychotic and anxiolytic

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This Item
R65205573301A12380
description

≥98% (HPLC), solid

description

solid, ≥98% (HPLC)

description

A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC₅₀ = 800 nM).

description

Pharmaceutical Analytical Impurity (PAI)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

form

solid

form

solid

form

solid

form

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

solubility

H2O: ~24 mg/mL

solubility

H2O: 0.2 mg/mL, ethanol: 7 mg/mL, DMSO: 7.3 mg/mL

solubility

DMSO: soluble

solubility

-

storage condition

desiccated

storage condition

-

storage condition

OK to freeze

storage condition

-

color

yellow

color

white to off-white

color

white

color

-


Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Codes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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