PRS3969

Anti-Sumo antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-GAP-modifying protein 1, Anti-SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), Anti-Ubiquitin-like protein 1, Anti-small-ubiquitin-like modifier 1
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD02096449
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (i), IF, IHC, WB
• Citations: 5

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: mouse, human, rat
• technique(s): immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
• UniProt accession no.: P63165
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... SUMO1(7341)

Description

General description

SUMO1 (small ubiquitin-related modifier) is also called as Pic1 (inner centromere protein-related protein), Ubl1 (ubiquitin-like protein), hSmt3 (human homolog 3), or sentrin. It is located in the nucleus. SUMO1 gene is located on human chromosome 2q33.

Immunogen

a 14 amino acid peptide from near the amino-terminus of human sumo.

Biochem/physiol Actions

Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It involves in mitochondrial fission.

Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It is involved in mitochondrial fission.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3969.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable