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765597

Gold nanoparticles

5 nm diameter, methyl terminated, PEG 2000 coated, OD 50, dispersion in H2O

Synonym(s):

Gold nanoparticles OMe terminated, Au NP OMe, Gold Colloid

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Size/SKUAvailabilityPrice
1 mL

Available to ship TODAYfromMILWAUKEE

$783.00
$587.25

About This Item

NACRES:
NA.23
UNSPSC Code:
12162002

$587.25

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material

PEG 2000

Quality Segment

form

dispersion in H2O, nanoparticles

packaging

poly bottle of 1 mL

OD

50

diameter

5 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

functional group

methoxy

storage temp.

2-8°C

General description

Gold nanoparticles (AuNPs) ranging from 2-200nm in diameter find applications in diverse fields.They show excellent biocompatibility and attractive physicochemical properties. Poly (ethylene) glycol (PEG) surface coatings on gold nanoparticles help in the reduction of protein adsorption, reduce nonspecific interactions with cells and greatly improve the pharmokinetics of these nanoparticles and reduce aggregation of the nanoparticles. PEG layer density depends inversely on the AuNP curvature. Denser coatings are possible on smaller AuNPs. The methyl group, being hydrophobic, acts as a protecting shield between the gold nanoparticles and the hydrophilic outer PEG coating and also leads to a further reduction of protein adsorption and macrophage uptake by the AuNPs.†††

Application

Several other specific applications have been listed below:
  • Since they adhere to cell membranes, AuNPs may find use in cellular and intracellular targeting in targeted drug delivery applications and may also be used in biodistribution studies.
  • AuNPs may also be used in photothermal therapy and radiotherapy.
  • AuNPs ranging from 10 to 250 nm, were studied to have been absorbed primarily by liver and spleen , when injected intravenously in rats.Whereas, 10 nm nanoparticles were distributed more broadly into various organs.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Features and Benefits

The PEG coating decreases the cytotoxicity and increases efficiency of GNPs in targeted drug delivery. PEG increases the stability of the nanoparticles and prevents agglomeration. Forms complexes easily with dyes and thiol ligands.

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This Item
765341765384765325
description

5 nm diameter, methyl terminated, PEG 2000 coated, OD 50, dispersion in H2O

description

20 nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H2O

description

40 nm diameter, amine functionalized, PEG 3000 coated, OD 50, dispersion in H2O

description

15 nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H2O

functional group

methoxy

functional group

amine

functional group

amine

functional group

amine

form

dispersion in H2O, nanoparticles

form

nanoparticles, dispersion in H2O

form

dispersion in H2O, nanoparticles

form

nanoparticles, dispersion in H2O

pH

6.0-8.0 (25 °C)

pH

6.0-8.0 (25 °C)

pH

6.0-8.0 (25 °C)

pH

6.0-8.0 (25 °C)

solubility

water: miscible

solubility

water: miscible

solubility

water: miscible

solubility

water: miscible

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

density

1.00 g/cm3

density

1.00 g/cm3

density

1.00 g/cm3

density

1.00 g/cm3


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Storage Class

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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