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56480

N-Hydroxysuccinimide

≥97.0% (T), for peptide synthesis

Synonym(s):

1-Hydroxy-2,5-pyrrolidinedione, HOSu, NHS

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25 g

Available to ship TODAYfromMILWAUKEE

$105.00
100 g

Available to ship TODAYfromMILWAUKEE

$201.00
1 kg

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$368.00

About This Item

Empirical Formula (Hill Notation):
C4H5NO3
CAS Number:
Molecular Weight:
115.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
228-001-3
MDL number:
Beilstein/REAXYS Number:
113913

$105.00


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Product Name

N-Hydroxysuccinimide, purum, ≥97.0% (T)

grade

purum

Quality Segment

assay

≥97.0% (T)

form

solid

reaction suitability

reaction type: Addition Reactions

mp

95-98 °C

application(s)

peptide synthesis

functional group

imide

SMILES string

ON1C(=O)CCC1=O

InChI

1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

InChI key

NQTADLQHYWFPDB-UHFFFAOYSA-N

Application

N-Hydroxysuccinimide (NHS) can be used in the following applications:
  • To synthesize N-succinimidyl 3-(2-pyridyldithio)-propionate, a heterobifunctional reagent useful for protein-protein conjugation and also to incorporate aliphatic thiols into proteins.
  • To synthesize NHS esters of long-chain fatty acids.
  • NHS can activate the phosphonic acid monolayers immobilized on titanium surface for binding with proteins.

Other Notes

may contain 1-3% succinic acid and/or succinic anhydride

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This Item
13067256485S9381
description

purum, ≥97.0% (T)

description

98%

description

≥98% (HPLC)

description

-

form

solid

form

solid

form

powder

form

powder or crystals

grade

purum

grade

-

grade

-

grade

-

assay

≥97.0% (T)

assay

98%

assay

≥98% (HPLC)

assay

99.1%

functional group

imide

functional group

imide

functional group

sulfonic acid, imide

functional group

-

mp

95-98 °C

mp

95-98 °C (lit.)

mp

-

mp

123-125 °C (lit.)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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