콘텐츠로 건너뛰기
Merck

다음으로 건너뛰기

R5010

Resveratrol

≥99% (HPLC)

동의어(들):

3,4′,5-Trihydroxy-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol

조직 및 계약 가격을 보려면 를 클릭합니다.

크기 선택

보기 변경
팩 크기/SKU재고 정보가격 (VAT 별도)
100 mg

오늘 배송 가능재고 수량 조회Seoul Warehouse South Korea

₩326,932
500 mg

오늘 배송 가능재고 수량 조회Seoul Warehouse South Korea

₩1,191,712

제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C14H12O3
CAS 번호:
Molecular Weight:
228.24
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:

₩326,932


오늘 배송 가능세부사항


맞춤 주문 요청하기
기술 서비스
도움이 필요하신가요? 저희 숙련된 과학자 팀이 도와드리겠습니다.
도움 문의


biological source

plant root (bushy knotweed)

Quality Segment

assay

≥99% (HPLC)

form

powder

solubility

acetone: 50 mg/mL, clear, faintly yellow

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

InChI key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

Gene Information

Application

Selective inhibitor of COX−1.
Resveratrol has been used:
  • in entrapment experiment
  • to study its neuroprotective effect on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent protein kinase II
  • as a standard in the assessment of stilbene content in grapevine leaf by in vivo fluorometry

Biochem/physiol Actions

Resveratrol is a phenolic phytoalexin found in grape skin and other plants. It has intracellular antioxidant activity and activates sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide (NAD+)-dependent histone deacetylase involved in mitochondrial biogenesis and the enhancement of peroxisome proliferator-g-activated receptor coactivator-1a (PGC-1a) and FOXO (forkhead box) activity. The anti-diabetic, neuroprotective and anti-adipogenic actions of resveratrol may be mediated via SIRT1 activation. Resveratrol has antiviral action against Herpes simplex virus-1 (HSV1) and HSV2. It also exhibits antitumor and phytoestrogenic biological activities. Resveratrol is known to prolong life in many species by mediating several physiological events.

Preparation Note

Soluble in ethanol, DMSO, and acetone. Only very slightly soluble in water (3 mg/100 mL).

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 1

이 품목
34092554325PHR2201
assay

≥99% (HPLC)

assay

-

assay

≥98% (HPLC)

assay

-

form

powder

form

-

form

solid

form

-

biological source

plant root (bushy knotweed)

biological source

-

biological source

-

biological source

-

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

-

application(s)

pharmaceutical small molecule

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

acetone: 50 mg/mL, clear, faintly yellow

solubility

-

solubility

DMSO: 50 mg/mL

solubility

-


Still not finding the right product?

Explore all of our products under Resveratrol


hcodes

Hazard Classifications

Aquatic Chronic 3

저장 등급

11 - Combustible Solids

flash_point_f

>392.0 °F - closed cup - (External MSDS)

flash_point_c

> 200.0 °C - closed cup - (External MSDS)

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

도움이 필요하시면 연락하세요. 고객 지원 부서

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문



질문

1–10 / 11 질문  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 답변
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      도움이 되었습니까?

  2. Can a resveratrol solution turn red?

    1 답변
    1. Solubility is tested in acetone, resulting in a faint yellow color. In acidic conditions, resveratrol can appear more reddish. In neutral or alkaline conditions, resveratrol will appear yellowish or colorless. Oxidation of resveratrol may also change its color, potentially leading to a reddish hue. Resveratrol is highly oxidizable and reacts readily with reactive oxygen species.

      도움이 되었습니까?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 답변
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      도움이 되었습니까?

  4. What is the solubility limit in ethanol ?

    1 답변
    1. This product is tested for solubility in acetone at 50 mg/mL. It is soluble in ethanol at 50 mg/mL and in DMSO at 16 mg/mL.

      도움이 되었습니까?

  5. does it expires? How long does powder last?

    1 답변
    1. This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

      도움이 되었습니까?

  6. 1- What is the iso-form (Cis or Trans) of the Resveratrol product R5010-500MG? 2- Do you have it emission spectra in 2-propanol and DMSO?

    1 답변
    1. As per the IUPAC name given, this product is a trans isoform. Unfortunately, emission spectra in 2-propanol and DMSO cannot be provided.

      도움이 되었습니까?

  7. What is the Department of Transportation shipping information for this product?

    1 답변
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      도움이 되었습니까?

  8. In what applications do researchers use Resveratrol, Product R5010?

    1 답변
    1. There are numerous applications for Resveratrol.  Several references indicate that it is used as a COX-1 inhibitor and a tumor repressor.

      도움이 되었습니까?

  9. How do I store Resveratrol, Product R5010, once in solution?

    1 답변
    1. A 5 mM solution of R5010 in ethanol has been found to be stable for 12 weeks when stored at 2-8°C and protected from light.Given a molecular weight of 228.24, a 5 mM solution is approximately 1.1 mg/mL.Reference: D.M. Goldberg, et al., J. Chrom. A, 708, 89-98 (1995).

      도움이 되었습니까?

  10. How do I dissolve Resveratrol, Product R5010?

    1 답변
    1. We test the solubility in ethanol at a concentration of 50 mg/mL.  It is also soluble at 16 mg/mL in DMSO (with sonication). It is practically insoluble in water.

      도움이 되었습니까?

1–10 / 11 질문  

후기

평점 값 없음

활성 필터