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324671

Potassium bis(trimethylsilyl)amide

95%

Synonym(s):

Hexamethyldisilazane potassium salt, Potassium hexamethyldisilazide

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Size/SKUAvailabilityPrice
5 g

Available to ship TODAY

$122.00
25 g

Available to ship TODAYfromMILWAUKEE

$174.00
100 g

Available to ship TODAYfromMILWAUKEE

$435.00

About This Item

Linear Formula:
[(CH3)3Si]2NK
CAS Number:
Molecular Weight:
199.48
UNSPSC Code:
12352111
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4006754
eCl@ss:
32150917
Assay:
95%
Form:
solid

$122.00


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Quality Segment

assay

95%

form

solid

density

0.877  g/cm3 at 20 °C

SMILES string

C[Si](C)(C)N([K])[Si](C)(C)C

InChI

1S/C6H18NSi2.K/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1

InChI key

IUBQJLUDMLPAGT-UHFFFAOYSA-N

General description

Potassium bis(trimethylsilyl)amide is commonly abbreviated as KHMDS with molecular formula [(CH3)3Si]2NK. It is widely used as Bronsted base in synthesis.

KHMDS is a base catalyst, that shows high activity and selectivity for the alkylation of alkylpyridines.

Application

Anionic initiator used in the preparation of poly(ethylene oxide). Sterically hindered base employed in selective cyclization reactions. Also used in the preparation of lanthanide complexes.

Features and Benefits

Potassium bis(trimethylsilyl)amide (KHMDS):
  • Easily available.
  • Good selectivity for the benzylic C−H bonds.
  • Good reactivity for sterically crowded C−H bonds.

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This Item
702722775061277304
description

95%

description

1 M in THF

description

1.0 M in 2-methyltetrahydrofuran

description

0.5 M in toluene

assay

95%

assay

-

assay

-

assay

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

form

solid

form

liquid

form

liquid

form

liquid

density

0.877  g/cm3 at 20 °C

density

0.915 g/mL at 25 °C

density

0.884 g/mL at 25 °C

density

0.877 g/mL at 25 °C


Pictograms

Corrosion

Signal Word

Danger

Hazard Codes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

supp_hazards

Storage Class

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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