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39410

4-(Dimethylamino)pyridine, polymer-bound

extent of labeling: ~3.0 mmol/g "DMAP" loading, matrix crosslinked with 2% DVB

Synonym(s):

4-(Dimethylamino)pyridine on Polystyrene, DMAP on PS, polymer bound DMAP

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Size/SKUAvailabilityPrice
5 g
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$181.00
25 g
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$729.00

About This Item

Empirical Formula (Hill Notation):
C8H8
CAS Number:
Molecular Weight:
104.15
UNSPSC Code:
12352128
PubChem Substance ID:
NACRES:
NA.22
MDL number:

$181.00


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reaction suitability

reaction type: solution phase peptide synthesis

Quality Segment

extent of labeling

~3.0 mmol/g "DMAP" loading

matrix

crosslinked with 2% DVB

anion traces

chloride (Cl-): ≤5000 mg/kg

General description

Polymer-bound 4-(dimethylamino)pyridine is used for improved derivatization of chiral and achiral aliphatic amines, amino alcohols and amino acids.

Application

Polymer-bound 4-(dimethylamino)pyridine is used as a supported base in the Michael addition and nitrous acid elimination process step involved in the synthesis of thiophene-2-carboxylates using β-nitroacrylates as starting materials, under a general and efficient continuous flow-based protocol. It also serves as a supported catalyst in the preparation of ω-nitro esters starting from cyclic 2-nitro ketones under solid heterogeneous catalysis.(5)

Other Notes

Polymer supported, recyclable acylation catalystcitationcitationcitation
Polymer supported, recyclable acylation catalyst

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This Item
472107632627493813
description

extent of labeling: ~3.0 mmol/g "DMAP" loading, matrix crosslinked with 2% DVB

description

extent of labeling: 3.5-5.0 mmol/g N loading, 1 % cross-linked with divinylbenzene

description

200-400 mesh, extent of labeling: 1.3-2.3 mmol/g loading, 1 % cross-linked with divinylbenzene

description

200-400 mesh, extent of labeling: 2.75-3.25 mmol/g loading, 1 % cross-linked

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

100

anion traces

chloride (Cl-): ≤5000 mg/kg

anion traces

-

anion traces

-

anion traces

-

extent of labeling

~3.0 mmol/g "DMAP" loading

extent of labeling

3.5-5.0 mmol/g N loading

extent of labeling

1.3-2.3 mmol/g loading

extent of labeling

2.75-3.25 mmol/g loading

matrix

crosslinked with 2% DVB

matrix

-

matrix

-

matrix

-

reaction suitability

reaction type: solution phase peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

reaction suitability

reactivity: alcohol reactive, reaction type: solution phase peptide synthesis

reaction suitability

reactivity: proton reactive, reaction type: solution phase peptide synthesis


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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