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764752

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)

PEG average Mn 5,000, PLGA Mn 55,000

Synonym(s):

PEG-PLGA, Polyethylene glycol, mPEG-b-PLGA, mPEG-b-PLGA

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Size/SKUAvailabilityPrice
1 g
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$357.00

About This Item

Linear Formula:
H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3
NACRES:
NA.23
UNSPSC Code:
12162002

$357.00


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description

typical PEG PDI < 1.1; overall PDI < 2.5

Quality Segment

form

pellets

feed ratio

lactide:glycolide 50:50

mol wt

PEG average Mn 5,000, PLGA Mn 55,000, average Mn 60,000 (total)

degradation timeframe

1-4 weeks

transition temp

Tg 10 °C(lit.), Tm 254-259 °C

PDI

<1.2

storage temp.

2-8°C

General description

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.

Application

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Features and Benefits

  • Good biocompatibility, low immunogenicity and good degradability.
  • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

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This Item
764817765139764825
description

PEG average Mn 5,000, PLGA Mn 55,000

description

average Mn (1100-1000-1100), lactide:glycolide 75:25

description

PEG average Mn 5,000, PLGA Mn 7,000

description

PEG Mn 2,000, PLGA Mn 4,500

form

pellets

form

semisolid

form

solid

form

pellets

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mol wt

PEG average Mn 5,000, PLGA Mn 55,000, average Mn 60,000 (total)

mol wt

average Mn (1100-1000-1100), PLGA average Mn 2,200, PEG average Mn 1,000

mol wt

PLGA Mn 7,000, average Mn 12,000 (total), PEG average Mn 5,000

mol wt

average Mn 6,500 (total), PEG Mn 2,000, PLGA Mn 4,500

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

description

typical PEG PDI < 1.1; overall PDI < 2.5

description

typical PEG PDI<1.1; overall PDI≤2.0 (THF, PS)

description

-

description

-

feed ratio

lactide:glycolide 50:50

feed ratio

lactide:glycolide 75:25

feed ratio

lactide:glycolide 50:50

feed ratio

lactide:glycolide 65:35


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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