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775797
Isopropylmagnesium bromide solution
0.75 M in THF
Synonym(s):
1-Methylethylmagnesium bromide, 2-Propylmagnesium bromide, iso-Propylmagnesium bromide, Bromoisopropylmagnesium
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
100 mL | Check Cart for Availability | $105.00 |
4 x 25 mL | Check Cart for Availability | $116.00 |
800 mL | Check Cart for Availability | $564.00 |
About This Item
form
solution
Quality Segment
reaction suitability
reaction type: Grignard Reaction
packaging
Sure/Seal™ of
concentration
0.75 M in THF
density
0.982 g/mL at 25 °C
storage temp.
2-8°C
SMILES string
CC(C)[Mg]Br
InChI
1S/C3H7.BrH.Mg/c1-3-2;;/h3H,1-2H3;1H;/q;;+1/p-1
InChI key
UCJIVFREPMUZDC-UHFFFAOYSA-M
Application
- Preparation of isopropylmagnesium bromide solutions: In this study, various concentrations of isopropylmagnesium bromide solutions were prepared, detailing their stability and reactivity for use in palladium-catalyzed cross-coupling reactions and other synthetic applications (Vulović et al., 2017).
- Reductive coupling of amides: This research discusses the reductive functionalization of tertiary amides using isopropylmagnesium bromide, providing a novel method for amine synthesis, which is crucial for pharmaceutical chemistry (Xie and Dixon, 2017).
- Synthesis of 1, 2, 3-triazoles: The study explores the use of isopropylmagnesium bromide in the synthesis of 1, 2, 3-triazoles through Grignard reactions, highlighting its role in protecting azides during the reaction process (Namioka et al., 2023).
- Disposable cartridge concept for Grignard reagents: This paper introduces a novel disposable cartridge for the on-demand synthesis of Grignard reagents, including isopropylmagnesium bromide, enhancing the safety and scalability of Grignard reactions (Berton et al., 2020).
Packaging
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description 0.75 M in THF | description 2.9 M in 2-methyltetrahydrofuran | description 0.5 M in THF | description 1.4 M in THF: toluene (1:3) |
| reaction suitability reaction type: Grignard Reaction | reaction suitability reaction type: Grignard Reaction | reaction suitability reaction type: Grignard Reaction | reaction suitability reaction type: Grignard Reaction |
| density 0.982 g/mL at 25 °C | density 1.112 g/mL at 25 °C | density 0.935 g/mL at 25 °C | density 1.018 g/mL at 25 °C |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 200 |
| concentration 0.75 M in THF | concentration 40 % (w/w), 2.9 M in 2-methyltetrahydrofuran | concentration 0.5 M in THF | concentration 1.4 M in THF: toluene (1:3) |
| storage temp. 2-8°C | storage temp. - | storage temp. - | storage temp. - |
| packaging Sure/Seal™ of | packaging Sure/Seal™ of | packaging Sure/Seal™ of | packaging Sure/Seal™ of |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3 - Water-react. 1
Target Organs
Central nervous system, Respiratory system
supp_hazards
Storage Class
4.3 - Hazardous materials which set free flammable gases upon contact with water
Flash Point (°F)
-22.0 °F - closed cup
Flash Point (°C)
-30 °C - closed cup
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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