Skip to Content
MilliporeSigma

Skip To

D4407

2-Deoxy-D-galactose

98%

Synonym(s):

2-Deoxy-D-lyxohexose

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 g
Check Cart for Availability
$324.00

About This Item

Empirical Formula (Hill Notation):
C6H12O5
CAS Number:
Molecular Weight:
164.16
UNSPSC Code:
12352201
NACRES:
NA.22
PubChem Substance ID:
EC Number:
217-765-3
Beilstein/REAXYS Number:
1723333
MDL number:

$324.00


Check Cart for Availability

​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

98%

form

powder

optical activity

[α]20/D +59.7°, c = 2 in H2O

color

white to off-white

mp

107 - 110 °C ((225 - 230 °F)), 107-110 °C (lit.)

SMILES string

OC[C@H]1OC(O)C[C@@H](O)[C@H]1O

InChI

1S/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2/t3-,4-,5?,6-/m1/s1

InChI key

PMMURAAUARKVCB-DUVQVXGLSA-N

General description

2-Deoxy-D-galactose is a glucose analog that shows a wide range of biological activities such as inhibition of glycolysis and thereby tumor growth, interference with the biosynthetic processing of glycoproteins, antiviral activity, and hepatotoxicity. It is being extensively studied as trapping agents for phosphate and uridylate in mammalian cells due to its ability to interfere in the phosphate and nucleotide metabolism.

Application


  • FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis.: This research investigates the role of 2-deoxy-D-galactose in modulating terminal fucosylation processes, revealing potential therapeutic pathways for treating renal fibrosis and enhancing the understanding of kidney disease mechanisms (Luo et al., 2023).

  • 2-D-gal Targets Terminal Fucosylation to Inhibit T-cell Response in a Mouse Skin Transplant Model.: Highlights the immunomodulatory potential of 2-deoxy-D-galactose in transplant medicine, showing how it can inhibit T-cell responses and contribute to the success of skin grafts, pointing towards new immunosuppressive treatments (Mao et al., 2023).

  • Inhibition of Aberrant α(1,2)-Fucosylation at Ocular Surface Ameliorates Dry Eye Disease.: Explores the therapeutic effects of 2-deoxy-D-galactose in treating dry eye disease by modulating specific fucosylation pathways, potentially opening new avenues for ocular surface treatment strategies (Yoon et al., 2021).

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
495077D3179661392
description

98%

description

98 atom % D

description

≥98% (GC), BioXtra

description

endotoxin tested, 98 atom % D

assay

98%

assay

99% (CP)

assay

≥98% (GC)

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

form

powder

form

solid

form

powder

form

solid

mp

107-110 °C (lit.), 107 - 110 °C ((225 - 230 °F))

mp

169-170 °C (lit.)

mp

146-147 °C (lit.)

mp

169-170 °C (lit.)

color

white to off-white

color

-

color

white

color

-

optical activity

[α]20/D +59.7°, c = 2 in H2O

optical activity

[α]25/D +79.0, c = 2 in H2O (trace NH4OH)

optical activity

-

optical activity

[α]25/D +79.0, c = 2 in H2O (trace NH4OH)


Still not finding the right product?

Explore all of our products under 2-Deoxy-D-galactose


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters