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8.52360

Fmoc-L-propargylglycine

Novabiochem®

Synonym(s):

Fmoc-L-propargylglycine, N-Fluorenemethoxycarbonyl-L-propargyl glycine

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Size/SKUAvailabilityPrice
1 g
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$386.00
5 g
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$1,570.00
$1,177.50

About This Item

Empirical Formula (Hill Notation):
C20H17NO4
CAS Number:
Molecular Weight:
335.35
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:

$386.00


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Quality Segment

product line

Novabiochem®

form

solid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

alkyne

storage temp.

15-25°C

SMILES string

N([C@@H](CC#C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C20H17NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h1,3-6,8-11,17-18H,7,12H2,(H,21,24)(H,22,23)/t18-/m0/s1

InChI key

DJGMNCKHNMRKFM-SFHVURJKSA-N

General description

Building block for the introduction by Fmoc SPPS of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)2/pyridine and heating to 60 °C using microwaves.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Optical rotation α 25/D (c=1 in DMF): -21.0 - -18.0 °
Solubility (1 mmole in 2 ml DMF): clearly soluble

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
852324852120852106
description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

description

Novabiochem®

form

solid

form

solid

form

solid

form

powder

functional group

alkyne

functional group

alkyne

functional group

amide

functional group

amine

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

product line

Novabiochem®

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

manufacturer/tradename

Novabiochem®

manufacturer/tradename

Novabiochem®

manufacturer/tradename

Novabiochem®

manufacturer/tradename

Novabiochem®


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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