Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

00200595

Quercetin dihydrate

primary reference standard

Synonym(s):

2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate, 3,3′,4′,5,7-Pentahydroxyflavone dihydrate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
50 mg

Available to ship TODAY

$697.00

About This Item

Empirical Formula (Hill Notation):
C15H10O7 · 2H2O
CAS Number:
6151-25-3
Molecular Weight:
338.27
EC Number:
204-187-1
UNSPSC Code:
85151701
NACRES:
NA.24
Colour Index Number:
75670
Beilstein/REAXYS Number:
317313
eCl@ss:
32120502

$697.00

Available to ship TODAYDetails

​
Request a Custom Order
​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

primary reference standard

form

powder

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

mp

>300 °C (lit.)

SMILES string

OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O

InChI

1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2

InChI key

GMGIWEZSKCNYSW-UHFFFAOYSA-N

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Reference standard in the analysis of herbal medicinal products.

Biochem/physiol Actions

Quercetin dihydrate is a flavonoid with anticancer activity.
Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle.

Other Notes

This compound is commonly found in plants of the genus: allium angelica arnica carum echinacea eucalyptus ginkgo glycyrrhiza lycium pimpinella primula sambucus silybum

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
Y0001009551600M1592409
Quercetin dihydrate primary reference standard

00200595

Quercetin dihydrate

Quercetin dihydrate European Pharmacopoeia (EP) Reference Standard

Y0001009

Quercetin dihydrate

Quercetin, Dihydrate A cell-permeable and reversible inhibitor of PIM1 kinase (IC50 = 43 nM), PI 3-K (IC50 = 3.8 µM) and phospholipase A2 (IC50 = 2 µM).

Millipore

551600M

Quercetin, Dihydrate

Quercetin United States Pharmacopeia (USP) Reference Standard

USP

1592409

Quercetin

description

primary reference standard

description

European Pharmacopoeia (EP) Reference Standard

description

A cell-permeable and reversible inhibitor of PIM1 kinase (IC50 = 43 nM), PI 3-K (IC50 = 3.8 µM) and phospholipase A2 (IC50 = 2 µM).

description

United States Pharmacopeia (USP) Reference Standard

grade

primary reference standard

grade

pharmaceutical primary standard

grade

-

grade

pharmaceutical primary standard

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

-

mp

>300 °C (lit.)

manufacturer/tradename

HWI

manufacturer/tradename

EDQM

manufacturer/tradename

Calbiochem®

manufacturer/tradename

USP

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

form

powder

form

-

form

solid

form

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

Still not finding the right product?

Explore all of our products under Quercetin dihydrate

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Hazard Codes

H301,H315,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

  1. What is the solubility, PKa, LogP, molecular weight and maximum absorption of 00200595 quercetin?

    1 answer

    1. The molecular weight of Quercetin hydrate is 302.24, on an anhydrous basis. The water content must be considered and is variable from lot to lot. The solubility, pKa, LogP, and absorption maximum are not determined. According to Drugbank the solubility in water is 261 ug/mL, the acidic pKa is 6.38 and the basic pKa is -4, and the LogP is 1.81 (per ALOGPS) and 2.16 (per Chemaxon). The absorbance maximum is not listed.

      See the link below for further information from Drugbank:
      https://go.drugbank.com/drugs/DB04216

      See the publication below for additional information on absorbance of Quercetin:
      https://www.jocpr.com/articles/determination-of-quercetin-by-uv-spectroscopy-as-quality-control-parameter-in-herbal-plant-cocculus-hirsutus.pdf

      Helpful?

Reviews

No rating value

Active Filters