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04471

(R)-(+)-α-Lipoic acid

analytical standard

Synonym(s):

(R)-(+)-1,2-Dithiolane-3-pentanoic acid, (R)-6,8-Dithiooctanoic acid, (R)-6,8-Thioctic acid

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Pack SizeSKUAvailabilityPrice
100 mg

Available to ship TODAYfromMILWAUKEE

$225.00

About This Item

Empirical Formula (Hill Notation):
C8H14O2S2
CAS Number:
1200-22-2
Molecular Weight:
206.33
NACRES:
NA.24
PubChem Substance ID:
329747929
UNSPSC Code:
85151701
MDL number:
MFCD01631142

$225.00

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grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

optical activity

[α]/D +115±5°, c = 1% in ethanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

48-52 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

OC(=O)CCCC[C@@H]1CCSS1

InChI

1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1

InChI key

AGBQKNBQESQNJD-SSDOTTSWSA-N

General description

α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.

Application

α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements[1] by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
07039085611368201
(R)-(+)-α-Lipoic acid analytical standard

Supelco

04471

(R)-(+)-α-Lipoic acid

(R)-(+)-α-Lipoic acid ≥98.0% (HPLC)

Sigma-Aldrich

07039

(R)-(+)-α-Lipoic acid

(S)-(−)-α -Lipoic acid ≥97% (HPLC)

Sigma-Aldrich

08561

(S)-(−)-α -Lipoic acid

Alpha Lipoic Acid United States Pharmacopeia (USP) Reference Standard

USP

1368201

Alpha Lipoic Acid

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

-

application(s)

-

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

neat

format

-

format

-

format

neat

Quality Level

100

Quality Level

100

Quality Level

100, 200

Quality Level

-

grade

analytical standard

grade

-

grade

-

grade

pharmaceutical primary standard

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4461
BCCJ1193
BCCJ7476
BCCF6166
BCCF6165

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Determination of lipoic acid in human plasma by HPLC-ECD using liquid-liquid and solid-phase extraction: Method development, validation and optimization of experimental parameters.
Khan, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 878(28), 2782-2788 (2010)
Determination of lipoic acid by flow-injection and high-performance liquid chromatography with chemiluminescence detection.
Wolyniec, et al.
Talanta, 96(2), 223-229 (2012)
High-performance liquid chromatographic assay for $\alpha$-lipoic acid and five of its metabolites in human plasma and urine.
Teichert, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 769(2), 269-281 (2002)
View All Related Papers

Global Trade Item Number

SKUGTIN
H41544-25ML04061833794739
H41544-4L04061833794746
804512100004022536385044
PHR1916-3X1.2ML04061835220847
804512602504022536622002
804512010004022536385037
804512250004022536385051
78891-1ML04061832947495
78891-5ML04061837242427
H41544-500ML04061833794753
04471-100MG04061838630667

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