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32417

Natamycin

VETRANAL®, analytical standard

Synonym(s):

Pimaricin, Natamycin

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Size/SKUAvailabilityPrice
50 mg

Available to ship TODAYfromMILWAUKEE

$180.00

About This Item

Empirical Formula (Hill Notation):
C33H47NO13
CAS Number:
7681-93-8
Molecular Weight:
665.73
E Number:
E235
PubChem Substance ID:
329754196
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
231-683-5
MDL number:
MFCD00135085

$180.00

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grade

analytical standard

Quality Segment

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1C\C=C\C=C\C=C\C=C\[C@@H](C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3\C=C\C(=O)O1)C[C@H](O)[C@H]2C(O)=O)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O

InChI

1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1

InChI key

NCXMLFZGDNKEPB-FFPOYIOWSA-N

General description

Natamycin is a polyene antibiotic that generally finds application as an antifungal agent as it lacks development of resistance and has a broad spectrum of activity. However, its mode of action is yet unclear, direct binding and isothermal titration calorimetry studies has revealed that natamycin binds specifically to ergosterol present in model membranes.
Natamycin shows activity against both molds and yeasts. It finds applications as a fungicidal and antibiotic preservative in the food industry.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Natamycin may be used as an analytical reference standard for the quantification of the analyte in wine samples using high-performance liquid chromatography coupled to electrospray ionization in positive mode high resolution mass spectrometry (HPLC-ESI-HR-MS) and reversed-phase high-performance liquid chromatography-tandem mass spectrometry technique (UHPLC-MS/MS).

Biochem/physiol Actions

An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
P9703P0440PHR1703
Natamycin VETRANAL®, analytical standard

Supelco

32417

Natamycin

Pimaricin from Streptomyces chattanoogensis, ≥95% (HPLC)

Sigma-Aldrich

P9703

Pimaricin

Pimaricin preparation ~2.5% (γ-irradiated Pimaricin), aqueous suspension

Sigma-Aldrich

P0440

Pimaricin preparation

Natamycin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1703

Natamycin

description

VETRANAL®, analytical standard

description

from Streptomyces chattanoogensis, ≥95% (HPLC)

description

~2.5% (γ-irradiated Pimaricin), aqueous suspension

description

Pharmaceutical Secondary Standard; Certified Reference Material

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

agriculture
environmental

application(s)

-

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

gas chromatography (GC): suitable, HPLC: suitable

format

neat

format

-

format

-

format

neat

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

300

grade

analytical standard

grade

-

grade

-

grade

certified reference material, pharmaceutical secondary standard

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

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