Key Documents

Meropenem trihydrate

Name: Meropenem trihydrate
Brand: SIAL
Price: 160 USD
Availability: InStock

VETRANAL^®, analytical standard

Synonym(s):

(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate

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Size/SKU	Availability	Price
25 mg	Check Cart for Availability	$160.00

About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₅N₃O₅S · 3H₂O

CAS Number:

119478-56-7

Molecular Weight:

437.51

NACRES:

NA.24

PubChem Substance ID:

329754224

UNSPSC Code:

41116107

MDL number:

MFCD08600005

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Properties

grade

analytical standard

Quality Segment

100

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

shipped in

wet ice

storage temp.

−20°C

SMILES string

O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N2C1=O)C(O)=O

InChI

1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1

InChI key

CTUAQTBUVLKNDJ-OBZXMJSBSA-N

Description

General description

Meropenem trihydrate (Meropenem) is a broad-spectrum carbapenem with antibacterial properties. It inhibits cell wall synthesis in both gram-negative and gram-positive bacteria.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Meropenem has been used as a reference standard in an experiment conducted to investigate the effects on in vivo efficacy caused due to chemical differences in three generic products of meropenem.

Meropenem penetrates cell walls and binds to penicillin-binding protein targets. It acts against aerobes and anaerobes including E. coli, Klebsiella, Clostridium, Enterococcus sp. It is a common cause of mild transient aminotransferase elevations and can rarely result in clinically apparent, cholestatic liver injury.

Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic active against both Gram-positive and Gram-negative bacteria.

Meropenem trihydrate is an ultra-broad spectrum beta-lactam antibiotic.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	Y0001252	M2574	1392454
Supelco 32460 Meropenem trihydrate	Y0001252 Meropenem trihydrate	Sigma-Aldrich M2574 Meropenem trihydrate	USP 1392454 Meropenem
description VETRANAL^®, analytical standard	description European Pharmacopoeia (EP) Reference Standard	description ≥98% (HPLC)	description United States Pharmacopeia (USP) Reference Standard
grade analytical standard	grade pharmaceutical primary standard	grade -	grade pharmaceutical primary standard
format neat	format neat	format -	format neat
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) -	technique(s) -
storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. -
shelf life limited shelf life, expiry date on the label	shelf life -	shelf life -	shelf life -
Quality Level 100	Quality Level -	Quality Level 100	Quality Level -

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Pictograms

GHS08

Signal Word

Danger

Hazard Codes

H317,H334

Precautionary Statements

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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Certificates of Analysis (COA)

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