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434760

Benzamidine hydrochloride

99%

Synonym(s):

Amidinobenzene hydrochloride, Benzamidinium chloride

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Size/SKUAvailabilityPrice
5 g

Available to ship TODAY

$78.50
25 g

Available to ship TODAY

$269.00

About This Item

Linear Formula:
C6H5C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
156.61
UNSPSC Code:
12352106
NACRES:
NA.77
PubChem Substance ID:
EC Number:
216-795-4
Beilstein/REAXYS Number:
3594959
MDL number:

$78.50


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Quality Segment

assay

99%

form

beads

mp

169-173 °C (lit.)

solubility

water: soluble

SMILES string

Cl.NC(=N)c1ccccc1

InChI

1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H

InChI key

LZCZIHQBSCVGRD-UHFFFAOYSA-N

Application

<ul>
<li><strong>Purification and characterization of a serine protease from organic dust and elucidation of its inductive effects on lung i</strong></li>
<li><strong>Preclinical testing of dabigatran in trypsin-dependent pancreatitis:</strong> This research uses Benzamidine hydrochloride to inhibit serine proteases in models of pancreatitis, highlighting its potential in preclinical studies to evaluate new therapeutic approaches for inflammatory and digestive disorders (Pesei et al., 2022).</li>
</ul>

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This Item
63226B6506242284
description

99%

description

-

description

≥99%

description

ACS reagent, ≥99.5%

assay

99%

assay

-

assay

≥99%

assay

≥99.5%

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

form

beads

form

-

form

powder

form

liquid

solubility

water: soluble

solubility

-

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

water: soluble

mp

169-173 °C (lit.)

mp

-

mp

86-88 °C (lit.)

mp

−6 °C (lit.)


Storage Class

11 - Combustible Solids

WGK

WGK 3

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–7 of 7 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. What is the stability of this product in solution at room temperature, i.e. what is the recommended expiry after the dilution is prepared?

    1 answer
    1. The stability this specific product in solution has not been evaluated. However, the 1M solution, available for sale as product 63226 is stored refrigerated at 2-8°C and is stable for at least 1 year.

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. What can Product 434760, Benzamidine hydrochloride, be used for?

    1 answer
    1. Benzamidine hydrochloride has been shown to act as a reversible inhibitor of trypsin, trypsin-like enzymes and serine proteases.

      Helpful?

  5. Does Product 434760, Benzamidine hydrochloride, contain waters of hydration?

    1 answer
    1. Sigma-Aldrich does not measure the water content directly of this product. However, based on the way the material is produced and handled, we would not expect any waters of hydration to be present. The corresponding hydrate product is found under Product No. B6506.

      Helpful?

  6. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  7. What is Product 434760, Benzamidine hydrochloride, soluble in?

    1 answer
    1. We would expect benzamidine hydrochloride to be soluble in water to at least 50 mg/mL. However, gentle heating may be required to solubilize it at this concentration.

      Helpful?

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