The preparation method of this product is considered proprietary.
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About This Item
Product Name
N,N′-Disuccinimidyl carbonate, purum, ≥95.0% (NMR)
grade
purum
Quality Segment
assay
≥95.0% (NMR)
form
powder
reaction suitability
reaction type: Carbonylations
impurities
~3% N-hydroxysuccinimide (NMR)
mp
190 °C (dec.) (lit.)
application(s)
peptide synthesis
functional group
imide
storage temp.
−20°C
SMILES string
O=C1CCC(=O)N1OC(=O)ON2C(=O)CCC2=O
InChI
1S/C9H8N2O7/c12-5-1-2-6(13)10(5)17-9(16)18-11-7(14)3-4-8(11)15/h1-4H2
InChI key
PFYXSUNOLOJMDX-UHFFFAOYSA-N
Application
- Various carbamate derivatives from primary and sterically hindered secondary alcohols by alkoxycarbonylation.
- Active carbonate resins from 4-hydroxymethylpolystyrene and 4-hydroxymethyl-3-nitrobenzamido resins via hydroxy functional groups.
- Aza-glycinyl dipeptides, important intermediates for the preparation of various azapeptides.
It may be also used:
- In the two-step preparation of 5-(6-(azidomethyl)nicotinamido)pentanoic acid, a copper-chelating picolyl azide derivative.
- To activate the hydroxyl group of the hapten, γ-hydroxyphenylbutazone (HPBZ) so that HPBZ can effectively bind with human serum albumin(HSA)-immunogen to form a hapten-protein conjugate.
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This Item | |||
|---|---|---|---|
| description purum, ≥95.0% (NMR) | description ≥95% | description suitable for fluorescence, ≥95.0% (HPLC) | description ≥98.0% (HPLC) |
| form powder | form powder or crystals | form powder | form powder |
| grade purum | grade - | grade - | grade - |
| assay ≥95.0% (NMR) | assay ≥95% | assay ≥95.0% (HPLC) | assay ≥98.0% (HPLC) |
| functional group imide | functional group imide | functional group - | functional group Fmoc, imide |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
| impurities ~3% N-hydroxysuccinimide (NMR) | impurities - | impurities - | impurities - |
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signalword
Warning
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
hcodes
Hazard Classifications
Acute Tox. 4 Oral
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What is the reagent used to synthesize N,N′-Disuccinimidyl carbonate other than triphosgene
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