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46256

Erythromycin A hydrate

VETRANAL®, analytical standard

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250 mg

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$80.70

About This Item

Empirical Formula (Hill Notation):
C37H67NO13 · xH2O
CAS Number:
207291-29-0
Molecular Weight:
733.93 (anhydrous basis)
MDL number:
MFCD16661001
UNSPSC Code:
41116107
PubChem Substance ID:
329757110
EC Number:
204-040-1
NACRES:
NA.24

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Technical Service
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grade

analytical standard

Quality Segment

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

N([C@@H]1[C@H]([C@@H](O[C@@H](C1)C)O[C@@H]2[C@H]([C@@H]([C@H](C(=O)O[C@@H]([C@]([C@@H]([C@H](C(=O)C(C[C@]2(O)C)C)C)O)(O)C)CC)C)O[C@@H]3O[C@H]([C@@H]([C@@](C3)(OC)C)O)C)C)O)(C)C.O.O

InChI

1S/C37H67NO13.2H2O/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;;/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;2*1H2/t18?,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;;/m1../s1

InChI key

IWGQNYZQLVGGCS-ZKSNWDMWSA-N

Application

Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site.

Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.

Preparation Note

This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.

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This Item
BP781E6376E1300000
Erythromycin A hydrate VETRANAL®, analytical standard

Supelco

46256

Erythromycin A hydrate

Erythromycin British Pharmacopoeia (BP) Reference Standard

BP781

Erythromycin

Erythromycin potency: ≥850 μg per mg

Sigma-Aldrich

E6376

Erythromycin

Erythromycin for microbiological assay, European Pharmacopoeia (EP) Reference Standard

E1300000

Erythromycin

description

VETRANAL®, analytical standard

description

British Pharmacopoeia (BP) Reference Standard

description

potency: ≥850 μg per mg

description

for microbiological assay, European Pharmacopoeia (EP) Reference Standard

application(s)

clinical testing

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

advanced drug delivery

application(s)

pharmaceutical (small molecule)

technique(s)

gas chromatography (GC): suitable, HPLC: suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

neat

format

neat

format

-

format

neat

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

-

grade

analytical standard

grade

pharmaceutical primary standard

grade

-

grade

pharmaceutical primary standard

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCJ6927
    BCBS7769V
    SZBE092XV
    BCCB8689

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