Triemethoprim in a solution of 52% N,N dimethylacetamide:48% propylene glycol at 50 mg/ml is stable when stored at 25° C. There is only a 10% degradation of trimethoprim under these conditions after 885 days.
46984
Trimethoprim
VETRANAL®, analytical standard
Synonym(s):
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine, NSC 106568
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| Size/SKU | Availability | Price |
|---|---|---|
250 mg | Estimated to ship onSeptember 14, 2026fromMILWAUKEE | $92.30 |
About This Item
Empirical Formula (Hill Notation):
C14H18N4O3
CAS Number:
Molecular Weight:
290.32
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
212-006-2
Beilstein/REAXYS Number:
625127
MDL number:
grade
analytical standard
Quality Segment
agency
EPA 1694
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycoplasma
application(s)
clinical testing
format
neat
mode of action
DNA synthesis | interferes, enzyme | inhibits
storage temp.
2-8°C
SMILES string
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
InChI
1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
InChI key
IEDVJHCEMCRBQM-UHFFFAOYSA-N
General description
Chemical structure: pyrimidine
Application
Primarily used as an antibacterial agent. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
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This Item | |||
|---|---|---|---|
| description VETRANAL®, analytical standard | description certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | description United States Pharmacopeia (USP) Reference Standard | description ≥99.0% (HPLC) |
| application(s) clinical testing | application(s) forensics and toxicology | application(s) pharmaceutical (small molecule) | application(s) - |
| technique(s) HPLC: suitable, gas chromatography (GC): suitable | technique(s) gas chromatography (GC): suitable | technique(s) - | technique(s) - |
| format neat | format neat | format neat | format - |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level 200 |
| grade analytical standard | grade certified reference material, TraceCERT® | grade pharmaceutical primary standard | grade - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C |
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Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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