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70709

Hydroxyectoine

≥95% (HPLC)

Synonym(s):

(4S,5S)-5-Hydroxy-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, THP(A)

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Size/SKUAvailabilityPrice
1 g
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$44.30
10 g
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$312.00

About This Item

Empirical Formula (Hill Notation):
C6H10N2O3
CAS Number:
Molecular Weight:
158.16
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
24112111
MDL number:

$44.30


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Quality Segment

assay

≥95% (HPLC)

form

solid

SMILES string

CC1=N[C@@H]([C@@H](O)CN1)C(O)=O

InChI

1S/C6H10N2O3/c1-3-7-2-4(9)5(8-3)6(10)11/h4-5,9H,2H2,1H3,(H,7,8)(H,10,11)/t4-,5-/m0/s1

InChI key

KIIBBJKLKFTNQO-WHFBIAKZSA-N

Other Notes

Stabilizer for enzymes and biological macromolecules

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Questions

  1. what is Hydroxyectoine used for? can i use it stabilize multiple antibodies in a dry format with polyols

    1 answer
    1. Hydroxyectoin is an ectoine used by many halophilic microorganisms to protect themselves against the extreme salt and temperature conditions in their natural environment. Ectoines have been shown to stabilize proteins, nucleic acids, membranes, and cells. They do not interfere with enzymatic and binding reactions and are highly compatible with cell metabolism.

      Please see the datasheet below for more information:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/398/586/70709dat.pdf

      Please see the link below to review a publication that may be helpful.
      https://www.sciencedirect.com/science/article/pii/S0301462214001409
      https://pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.0c00395
      https://www.sigmaaldrich.com/search/70709?focus=papers&page=1&perpage=30&sort=relevance&term=70709&type=citation_search

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