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74601

3,3′-Diindolylmethane

analytical standard

Synonym(s):

3,3′-Bisindolylmethane, DIM

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Size/SKUAvailabilityPrice
100 mg

Estimated to ship onDecember 10, 2026fromSAINT LOUIS

$159.00

About This Item

Empirical Formula (Hill Notation):
C17H14N2
CAS Number:
1968-05-4
Molecular Weight:
246.31
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD00195766

$159.00

Estimated to ship onDecember 10, 2026Details

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grade

analytical standard

Quality Segment

100

assay

≥97.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34

InChI

1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2

InChI key

VFTRKSBEFQDZKX-UHFFFAOYSA-N

General description

3,3′-Diindolylmethane, a dimer of indole-3-carbinol, is a component of cruciferous vegetables. It is known to exhibit anticancer effects.

Application

3,3′-Diindolylmethane may be used as a model substrate to analyze the role of 3,3′-diindolylmethane in inducing apoptosis in human cancer cells.

Biochem/physiol Actions

Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor. The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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This Item
D956876854T3405
3,3′-Diindolylmethane analytical standard

Supelco

74601

3,3′-Diindolylmethane

3,3′-Diindolylmethane ≥98% (HPLC)

Sigma-Aldrich

D9568

3,3′-Diindolylmethane

(S)-(−)-5,5′-Dichloro-2,2′-bis(diphenylphosphino)-6,6′-dimethoxy-1,1′-biphenyl ≥97.0% (H-NMR)

Sigma-Aldrich

76854

(S)-(−)-5,5′-Dichloro-2,2′-bis(diphenylphosphino)-6,6′-dimethoxy-1,1′-biphenyl

3,3′,5,5′-Tetramethylbenzidine dihydrochloride tablet, 1 mg substrate per tablet

Sigma-Aldrich

T3405

3,3′,5,5′-Tetramethylbenzidine dihydrochloride

description

analytical standard

description

≥98% (HPLC)

description

≥97.0% (H-NMR)

description

tablet, 1 mg substrate per tablet

grade

analytical standard

grade

-

grade

-

grade

-

format

neat

format

-

format

-

format

-

application(s)

food and beverages

application(s)

-

application(s)

-

application(s)

-

assay

≥97.5% (HPLC)

assay

≥98% (HPLC)

assay

≥97.0% (H-NMR)

assay

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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