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S9876

Sulfathiazole

Synonym(s):

2-Sulfanilamidothiazole, 4-Amino-N-(2-thiazolyl)benzenesulfonamide, N1-(2-Thiazolyl)sulfanilamide

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Size/SKUAvailabilityPrice
100 g

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$177.00

About This Item

Empirical Formula (Hill Notation):
C9H9N3O2S2
CAS Number:
Molecular Weight:
255.32
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-771-5
Beilstein/REAXYS Number:
226178
MDL number:

$177.00


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grade

analytical standard

Quality Segment

agency

EPA 1694

form

powder

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

mp

200-202 °C (lit.)

application(s)

clinical testing

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2nccs2

InChI

1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)

InChI key

JNMRHUJNCSQMMB-UHFFFAOYSA-N

General description

Sulfathiazole is a broad-spectrum antibacterial drug, belonging to the class of sulfonamides, used in veterinary and human medication for the treatment of infections. It is also involved in promoting growth of livestock and fish.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfathiazole is used as an analytical reference standard for the quantification of the analyte in meat, and honey samples using different chromatography techniques.

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

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description

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description

VETRANAL®, analytical standard

description

European Pharmacopoeia (EP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

technique(s)

HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable, HPLC: suitable, chromatography: suitable

technique(s)

-

technique(s)

-

application(s)

clinical testing

application(s)

clinical testing

application(s)

pharmaceutical (small molecule)
pharmaceutical

application(s)

pharmaceutical
pharmaceutical (small molecule)

form

powder

form

-

form

-

form

-

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

-

grade

analytical standard

grade

analytical standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

agency

EPA 1694

agency

EPA 1694

agency

-

agency

USP


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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 2

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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Questions

Reviews

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    • Review 1
    • Votes 2
    2 out of 5 stars.

    Required extra work

    Needed to be recrystallized - MS showed contamination with Na.

    Helpful?

    1. Response from MilliporeSigma:

      Thank you for your review. This product is designated for research and laboratory use and undergoes basic qualtiy control testing. The minimum purity of any given lot will be 98% by HPLC. We do not further identify the impurities nor do we set minimum specifications on any potential contaminant. It is possible there there are trace amounts of residual salts and/or solvents which may interfere with more sensitive applications. We encourage customers who experience problems with our products to call or email us for additional technical support. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.