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01640

Acridine

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

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10 g

Estimated to ship TODAYfromMILWAUKEE

$143.00
$100.10

About This Item

Empirical Formula (Hill Notation):
C13H9N
CAS Number:
260-94-6
Molecular Weight:
179.22
PubChem Substance ID:
329747337
eCl@ss:
39210107
UNSPSC Code:
12171500
NACRES:
NA.32
EC Number:
205-971-6
MDL number:
MFCD00005025
Beilstein/REAXYS Number:
120200

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product line

BioReagent

Quality Level

100

assay

≥97.0% (HPLC)

bp

346 °C (lit.)

mp

106-111 °C, 107-110 °C (lit.)

solubility

ethanol: 0.5 g/10 mL, clear (hot), carbon disulfide: soluble, diethyl ether: soluble, ethanol: soluble, hydrocarbons: soluble

fluorescence

λex 360 nm; λem 417 nm in ethanol

suitability

suitable for fluorescence

SMILES string

c1ccc2nc3ccccc3cc2c1

InChI

1S/C13H9N/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12/h1-9H

InChI key

DZBUGLKDJFMEHC-UHFFFAOYSA-N

Application

The fluorescence intensity, fluorescence quantum yield, time of decay, and lifetime are dependent upon the solvent. For example, the fluorescence intensity varies from being moderately strong in aqueous solution and very weak in hydrocarbon solvents. Additionally, the quantum yield has been demonstrated to increase with decreasing temperatures, for all solvent conditions.

Analysis Note

In addition to the emission maximum at 417 nm, there are lower maxima at 435, 400 and 460 nm.

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This Item
A23609I3636235474
Acridine BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

Sigma-Aldrich

01640

Acridine

Acridine ≥96.5% (HPLC)

Sigma-Aldrich

A23609

Acridine

Acridine Mutagen ICR 191

Sigma-Aldrich

I3636

Acridine Mutagen ICR 191

Acridine Orange base Dye content 75 %

Sigma-Aldrich

235474

Acridine Orange base

suitability

suitable for fluorescence

suitability

-

suitability

suitable for Ames test in Salmonella and E. coli (Frameshift mutagenic standard)

suitability

-

fluorescence

λex 360 nm; λem 417 nm in ethanol

fluorescence

-

fluorescence

-

fluorescence

-

solubility

ethanol: 0.5 g/10 mL, clear (hot), diethyl ether: soluble, hydrocarbons: soluble, carbon disulfide: soluble, ethanol: soluble

solubility

-

solubility

DMSO: soluble

solubility

1 M HCl: 1 mg/mL, clear

assay

≥97.0% (HPLC)

assay

≥96.5% (HPLC), 96.5-103.5% (perchloric acid titration)

assay

-

assay

-

product line

BioReagent

product line

-

product line

-

product line

-

mp

106-111 °C, 107-110 °C (lit.)

mp

107-110 °C (lit.)

mp

-

mp

165 °C (dec.) (lit.)

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pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2932
BCCL6403
BCCL8333
BCCL1517
BCCK5292

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J S Plested et al.
Infection and immunity, 69(5), 3203-3213 (2001-04-09)
A recently described flow cytometric opsonophagocytic assay (OPA) was adapted to quantify the functional activity of serum antibodies specifically directed against serogroup B inner core lipopolysaccharide (LPS) of Neisseria meningitidis. The percentage of human peripheral polymorphonuclear leukocytes and monocytes (PMNms)
Subnanosecond Time-Resolved Fluorescence of Acridine in Solution
Diverdi, L. A., and Topp, M. R.
The Journal of Physical Chemistry, 88, 3447-3447 (1984)
Yoshiki Kobayashi et al.
Respiratory research, 17, 30-30 (2016-03-26)
We have recently reported that protein phosphate 2A (PP2A) inactivation resulted in increased phosphorylation of the mitogen-activated protein kinase (MAPK) c-Jun N-terminal kinase 1 (JNK1) and glucocorticoid receptors (GR) at Ser(226), thereby reducing GR nuclear translocation and causing corticosteroid insensitivity
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Global Trade Item Number

SKUGTIN
T21105-50G04061831836981
T21105-10G04061831827545
01640-10G04061838609540
01640-1G04061826678374
01640-50G04061838609557

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