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N-Ethylmaleimide

Name: <I>N</I>-Ethylmaleimide
Brand: SIGMA
Price: 147 CAD

purum p.a., ≥99.0% (HPLC)

Synonym(s):

NEM

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Pack Size	SKU	Availability	Price
5 g		Please contact Customer Service for Availability	$147.00
25 g		Please contact Customer Service for Availability	$547.00

About This Item

Empirical Formula (Hill Notation):

C₆H₇NO₂

CAS Number:

128-53-0

Molecular Weight:

125.13

NACRES:

NA.26

PubChem Substance ID:

329747901

UNSPSC Code:

12352209

EC Number:

204-892-4

MDL number:

MFCD00005509

Beilstein/REAXYS Number:

112448

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Properties

grade

purum p.a.

Quality Level

200

assay

≥99.0% (HPLC)

ign. residue

≤0.05%

bp

210 °C (lit.)

mp

43-46 °C

anion traces

chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤100 mg/kg

cation traces

Ca: ≤50 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, K: ≤100 mg/kg, Na: ≤100 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg

storage temp.

2-8°C

SMILES string

CCN1C(=O)C=CC1=O

InChI

1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

InChI key

HDFGOPSGAURCEO-UHFFFAOYSA-N

Gene Information

human ... SLC6A3(6531), SLC6A4(6532)

Description

Application

N-Ethylmaleimide has been used to measure low molecular weight thiols bound to plasma proteins.

Reagent for the covalent modification of cysteine residues in proteins.

Biochem/physiol Actions

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.

Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

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This Item	04259	E1271	34115-M
Sigma-Aldrich 04260 N-Ethylmaleimide	Sigma-Aldrich 04259 N-Ethylmaleimide	Sigma-Aldrich E1271 N-Ethylmaleimide	Millipore 34115-M N-Ethylmaleimide
grade purum p.a.	grade -	grade -	grade -
assay ≥99.0% (HPLC)	assay ≥99.0% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
mp 43-46 °C	mp 43-46 °C (lit.), 44-47 °C	mp 43-46 °C (lit.)	mp -
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 10-30°C
anion traces chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤100 mg/kg	anion traces chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤100 mg/kg	anion traces chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%	anion traces -

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pictograms

GHS06,GHS05

signalword

Danger

hcodes

H300,H311,H314,H317

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

163.2 °F - closed cup

flash_point_c

72.9 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

pcodes

P260 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

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Global Trade Item Number

SKU	GTIN
93598-100MG	04061833282946
8048120500	04022536386508
8048129050	04022536386515
8048120100	04022536386492
I29204-1KG	04061833848784
I29204-100G	04061833848777
04260-5G-F	04061838629319
04260-25G-F	04061838629302

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