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8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt

Name: 8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt
Brand: SIGMA
Price: 268 EUR

suitable for fluorescence, BioReagent, ≥96.0% (HPCE)

Synonym(s):

1,3,6-Pyrenetrisulfonic acid, 8-amino trisodium salt, APTS, Trisodium 8-aminopyrene-1,3,6-trisulfonate

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Pack Size	SKU	Availability	Price
5 mg		Please contact Customer Service for Availability	€268.00
25 mg		Please contact Customer Service for Availability	€826.00

About This Item

Empirical Formula (Hill Notation):

C₁₆H₈NNa₃O₉S₃

CAS Number:

196504-57-1

Molecular Weight:

523.40

UNSPSC Code:

12352106

PubChem Substance ID:

329748761

NACRES:

NA.32

MDL number:

MFCD00674494

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Properties

product line

BioReagent

Quality Level

200

assay

≥96.0% (HPCE)

mp

≥250 °C (lit.)

solubility

DMF: soluble, DMSO: soluble, H₂O: soluble

fluorescence

λ_ex 420 nm; λ_em 500 nm in 0.1 M Tris pH 7.4 (quenching with Vitamin B₁), λ_ex 488 nm; λ_em 520 nm(lit.)

suitability

suitable for fluorescence

SMILES string

[Na+].[Na+].[Na+].Nc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H11NO9S3.3Na/c17-11-5-12(27(18,19)20)8-3-4-10-14(29(24,25)26)6-13(28(21,22)23)9-2-1-7(11)15(8)16(9)10;;;/h1-6H,17H2,(H,18,19,20)(H,21,22,23)(H,24,25,26);;;/q;3*+1/p-3

InChI key

XSTNYACEWLNWPY-UHFFFAOYSA-K

Description

Application

Fluorescent label for saccharides and glycoproteins.[1]

APTS is a fluorescence reagent that has been demonstrated to have a high level of detection sensitivity for sugars The LOD for APTS-derivatized sugars has been shown to be 0.4 nM when using a 488 nm argon-ion laser. The multi-anionic nature of APTS makes it ideal for the studies of carbohydrate molecules and small hormone molecules by high resolution capillary electrophoresis.

Fluorescent label for glycoproteins and saccharides.

Other Notes

Fluorescent probe for derivatising sugars

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This Item	08658	A7222	700319P
Sigma-Aldrich 09341 8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt	Sigma-Aldrich 08658 8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt	Sigma-Aldrich A7222 8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt	Avanti 700319P Chenodeoxycholic acid disulfate trisodium salt
suitability suitable for fluorescence	suitability suitable for fluorescence	suitability -	suitability -
fluorescence λ_ex 420 nm; λ_em 500 nm in 0.1 M Tris pH 7.4 (quenching with Vitamin B₁), λ_ex 488 nm; λ_em 520 nm(lit.)	fluorescence λ_ex 356 nm; λ_em 512 nm in 0.1 M phosphate pH 7.0	fluorescence -	fluorescence -
solubility DMF: soluble, H₂O: soluble, DMSO: soluble	solubility 15% acetic acid: soluble, H₂O: soluble	solubility -	solubility -
assay ≥96.0% (HPCE)	assay ≥90% (CE)	assay ≥96.0% (HPCE)	assay >99% (TLC)
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
product line BioReagent	product line BioReagent	product line -	product line -

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Articles

Glycan Labeling

Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.

Sialic acid-specific affinity chromatography for the separation of erythropoietin glycoforms using serotonin as a ligand.

M Meininger et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1012-1013, 193-203 (2016-02-07)

Recombinant human erythropoietin (rhEPO) is an important CHO cell-derived glycoprotein and the degree of sialylation of this hormone is crucial for its in vivo bioactivity. In order to improve the purification process serotonin as a potential affinity ligand was tested

R.A. Evangelista et al.

Analytical Chemistry, 67, 2239-2239 (1995)

Delivery of Formulated Industrial Enzymes with Acoustic Technology.

Jennifer Dorcas Hwang et al.

Journal of laboratory automation, 21(1), 153-165 (2015-07-15)

Industrial enzymes are instrumental in many applications, including carbohydrate processing, fabric and household care, biofuels, food, and animal nutrition, among others. Enzymes have to be active and stable not only in harsh application conditions, but also during shipment and storage.

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Global Trade Item Number

SKU	GTIN
E14705-5G	04061837329913
E14705-25G	04061837329906
09341-5MG	04061838656179
09341-25MG	04061838656148

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