This product may be stored at room temperature, tightly closed, protected from light, and under inert gas. The solution stability has not been determined. However, various sources indicate that solutions prepared in Methanol, DMSO, Dimethylformamide, and Acetonitrile are stable up to 1 month when stored in aliquots at -20°C. This information has not been validated.
40227
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine
suitable for fluorescence, ≥97.0% (HPLC)
Synonym(s):
2-(Dimethylamino)-6-dodecanoylnaphthalene, Laurdan, N,N-Dimethyl-6-dodecanoyl-2-naphthylamine
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 mg | Please contact Customer Service for Availability | $653.00 |
About This Item
Empirical Formula (Hill Notation):
C24H35NO
CAS Number:
Molecular Weight:
353.54
UNSPSC Code:
12352116
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
7379104
Quality Level
assay
≥97.0% (HPLC)
mp
88 °C (lit.)
solubility
DMF: soluble, acetonitrile: soluble, methanol: soluble
fluorescence
λex 366 nm; λem 497 nm in methanol
suitability
suitable for fluorescence
SMILES string
CCCCCCCCCCCC(=O)c1ccc2cc(ccc2c1)N(C)C
InChI
1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3
InChI key
JHDGGIDITFLRJY-UHFFFAOYSA-N
Application
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine (Laurdan) is a fluorescent probe used to study membrane structure, order and dynamic processes such as fluidity.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Fluorescent membrane probe[1]
1 of 1
This Item | |||
|---|---|---|---|
| suitability suitable for fluorescence | suitability suitable for fluorescence | suitability - | suitability - |
| fluorescence λex 366 nm; λem 497 nm in methanol | fluorescence λex 361 nm; λem 498 nm in methanol | fluorescence - | fluorescence - |
| solubility DMF: soluble, methanol: soluble, acetonitrile: soluble | solubility DMF: soluble, acetone: soluble, acetonitrile: soluble, methanol: soluble | solubility - | solubility - |
| assay ≥97.0% (HPLC) | assay ≥98.0% (HPLC) | assay ≥98.0% (GC) | assay 99% |
| mp 88 °C (lit.) | mp - | mp -70 °C | mp - |
| Quality Level 100 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
Keita Hayashi et al.
Colloids and surfaces. B, Biointerfaces, 87(1), 28-35 (2011-05-31)
The surface properties of Span 80 vesicles at various cholesterol contents, together with those of various liposomes, were characterized by using fluorescence probes. The membrane fluidity of the Span 80 vesicles was measured by 1,6-diphenyl-1.3.5-hexatriene (DPH) and trimethlyammonium-DPH (TMA-DPH), and
L A Bagatolli et al.
Biochimica et biophysica acta, 1325(1), 80-90 (1997-04-03)
Laurdan (6-dodecanoyl-2-dimethylamine-naphthalene) is a fluorescent membrane probe of recent characterization. It was shown that this probe discriminates between phase transitions, phase fluctuations and the coexistence of phase domains in phospholipid multilamellar aggregates. We measured the excitation and emission generalized polarization
Núria Amigó et al.
Scientific reports, 6, 19249-19249 (2016-01-19)
Recent studies have shown that pharmacological increases in HDL cholesterol concentrations do not necessarily translate into clinical benefits for patients, raising concerns about its predictive value for cardiovascular events. Here we hypothesize that the size-modulated lipid distribution within HDL particles
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 40227-100MG | 04061833646359 |
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How to store Product No. 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan) in original packaging and as stock solution?
1 answer-
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the solubility of Product No. 40227(6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?
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Product 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine) is soluble in N,N-dimethylformamide (DMF), methanol and acetonitrile. It is also reported to be soluble in chloroform, according to Journal of Biological Chemistry, 248, 40186-40197 (2003).
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What are the spectral properties (excitation and emission maxima) of 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, Laurdan, Product 40227?
1 answer-
The spectral properties of 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine are: ?ex 366 nm; ?em 497 nm in methanol.
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What is the appearance of Product No. 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?
1 answer-
Product 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine) is described as powder to fine flakes.
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What are some of the physical properties of Product No. 40227 (6-Dodecanoyl-N,N-dimethyl-2-naphthylamine, also known as Laurdan)?
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The physical properties of 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine are:Boiling Point: 497.4 °C at atmospheric pressure (760 mm Hg)Flash Point: 177.4 °CMelting Point: 88°C(lit.)Density: 0.987 g/cm3Vapor Pressure: 4.95-10 mm Hg at 25°CRefractive Index: 1.553
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