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51120

Guanosine 5′-triphosphate sodium salt hydrate

≥90% (HPLC), powder

Synonym(s):

GTP, GTP-Na⁺ hydrate, 5′-GTP-Na2

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Size/SKUAvailabilityPrice
25 mg
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$74.60
100 mg
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$178.00
1 g
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$889.00

About This Item

Empirical Formula (Hill Notation):
C10H16N5O14P3 · xNa+ · yH2O
CAS Number:
Molecular Weight:
523.18 (anhydrous free acid basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
252-847-2
MDL number:
Beilstein/REAXYS Number:
4113439
Assay:
≥90% (HPLC)
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless
Storage temp.:
−20°C

$74.60


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Product Name

Guanosine 5′-triphosphate sodium salt hydrate, ≥90% (HPLC)

Quality Segment

assay

≥90% (HPLC)

form

powder

optical activity

[α]20/D −24±2°, c = 1% in 0.5 M Na2HPO4

impurities

≤3 mol/mol water (NMR)

solubility

water: 50 mg/mL, clear, colorless

shipped in

wet ice

storage temp.

−20°C

SMILES string

O.O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H16N5O14P3.2Na.2H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;2*1H2/q;2*+1;;/p-2/t3-,5-,6-,9-;;;;/m1..../s1

InChI key

HPLNHYUZFVUXFJ-ZVQJTLEUSA-L

General description

Guanosine 5′-triphosphate (GTP) is a purine trinucleotide. GTP is a substrate for a wide range of G-protein coupled receptor (GPCR) GTPases, as well as cell signaling and cycling-associated guanine nucleotide exchange factors (GEF). See product G3776 for RNA polymerase transcription and DNA or RNA biosynthesis applications.

Application

Guanosine 5′-triphosphate sodium salt hydrate has been used:
  • as a component of the internal solution for astrocyte patch-clamp to monitor astrocyte calcium activity from mouse amygdala slices.
  • in a solution for channel current recording in cell lines using a voltage-clamp technique.
  • to prepare internal recording solution for injectoporation to deliver genes to mechanosensory hair cells.
  • promoting the formation of G interface-mediated homodimers of human septin during the analysis of its oligomerization state by analytical size exclusion chromatography (SEC).

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This Item
10106399001G8877G5884
description

≥90% (HPLC)

description

>90% (HPLC), crystals, pkg of 250 mg

description

≥95% (HPLC), powder

description

~95% (HPLC), powder

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

200

form

powder

form

crystals

form

powder

form

powder

assay

≥90% (HPLC)

assay

>90% (HPLC)

assay

≥95% (HPLC)

assay

~95% (HPLC)

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

solubility

water: 50 mg/mL, clear, colorless

solubility

-

solubility

H2O: 50 mg/mL

solubility

H2O: 100 mg/mL

shipped in

wet ice

shipped in

-

shipped in

dry ice

shipped in

dry ice


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type N95 (US)



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