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H4890

Anti-Human Hemoglobin antibody produced in rabbit

whole antiserum

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2 mL
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497,00 €

A propos de cet article

UNSPSC Code:
12352203
NACRES:
NA.43
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i)
Citations:
18

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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

indirect ELISA: 1:8,000

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HBB(3043)

General description

HBB (hemoglobin subunit β) codes for a β globin that consists of three exons. This gene is located on human chromosome 11p15. HBB is a serum protein that belongs to the histone-like protein family.

Immunogen

Hemoglobin isolated from normal adult human red blood cells and treated to remove lipoproteins.

Application

Anti-Human Hemoglobin antibody has been used in pulse chase experiments and western blotting.
Anti-Human Hemoglobin antibody produced in rabbit was used for immunoblotting using crude human cerebellar protein extracts and membrane extracts of human RBC. It was used for immunohistochemistry of human tongue cancer samples.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

HBB (hemoglobin subunit β) participates in oxygen transport from the lung to various peripheral tissues. Mutation in HBB result in Sickle cell disease (SCD). Overexpression of HBB has been observed in patients with periodontal disease.
Hemoglobin (Hb) is oxygen-binding metalloprotein that is present in the red blood cells. The most abundant Hb is HbA tetramer that is made up of two α, two β chains and the nonprotein heme group. The heme group contains iron ion and a porphyrin ring. Mutations in Hb gene result in hemoglobinopathies, the best known being sickle-cell disease and thalassemias.

Preparation Note

treated to remove lipoproteins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Cet article
WH0003043M1HPA043234A8326
biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

antibody form

whole antiserum

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

whole antiserum

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

UniProt accession no.

P68871

UniProt accession no.

P68871

UniProt accession no.

P68871

UniProt accession no.

P05067

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

shipped in

dry ice

clone

polyclonal

clone

2H3, monoclonal

clone

polyclonal

clone

polyclonal


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Classe de stockage

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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