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Anti-Human Hemoglobin antibody produced in rabbit

Name: Anti-Human Hemoglobin antibody produced in rabbit
Brand: SIGMA
Price: 58696.8 INR

whole antiserum

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2 mL	Please contact Customer Service for Availability	₹58,696.80

About This Item

UNSPSC Code:

12352203

NACRES:

NA.43

MDL number:

MFCD00162411

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i)

Citations:

₹58,696.80

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

human

technique(s)

indirect ELISA: 1:8,000

UniProt accession no.

P68871

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HBB(3043)

Description

General description

HBB (hemoglobin subunit β) codes for a β globin that consists of three exons. This gene is located on human chromosome 11p15. HBB is a serum protein that belongs to the histone-like protein family.

Immunogen

Hemoglobin isolated from normal adult human red blood cells and treated to remove lipoproteins.

Application

Anti-Human Hemoglobin antibody has been used in pulse chase experiments and western blotting.

Anti-Human Hemoglobin antibody produced in rabbit was used for immunoblotting using crude human cerebellar protein extracts and membrane extracts of human RBC. It was used for immunohistochemistry of human tongue cancer samples.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

HBB (hemoglobin subunit β) participates in oxygen transport from the lung to various peripheral tissues. Mutation in HBB result in Sickle cell disease (SCD). Overexpression of HBB has been observed in patients with periodontal disease.

Hemoglobin (Hb) is oxygen-binding metalloprotein that is present in the red blood cells. The most abundant Hb is HbA tetramer that is made up of two α, two β chains and the nonprotein heme group. The heme group contains iron ion and a porphyrin ring. Mutations in Hb gene result in hemoglobinopathies, the best known being sickle-cell disease and thalassemias.

Preparation Note

treated to remove lipoproteins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	WH0003043M1	HPA043234	H2539
Sigma-Aldrich H4890 Anti-Human Hemoglobin antibody produced in rabbit	Sigma-Aldrich WH0003043M1 Monoclonal Anti-HBB antibody produced in mouse	Sigma-Aldrich HPA043234 Anti-HBB antibody produced in rabbit	Sigma-Aldrich H2539 Anti-HAP40 antibody produced in rabbit
description whole antiserum	description clone 2H3, purified immunoglobulin, buffered aqueous solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description affinity isolated antibody, buffered aqueous solution
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form whole antiserum	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 200
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
clone polyclonal	clone 2H3, monoclonal	clone polyclonal	clone polyclonal

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Key Documents

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Anti-Human Hemoglobin antibody produced in rabbit

whole antiserum

Select a Size

About This Item

H4890-2ML

₹58,696.80

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

contains

species reactivity

technique(s)

UniProt accession no.

shipped in

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Application

Biochem/physiol Actions

Preparation Note

Disclaimer

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Storage Class

wgk

flash_point_f

flash_point_c

Documentation

Certificates of Analysis (COA)

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