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HPA004331

Anti-CYP4B1 antibody produced in rabbit

Name: Anti-CYP4B1 antibody produced in rabbit
Brand: SIGMA
Price: 881 CAD

Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonyme(s) :

Anti-CYPIVB1 antibody produced in rabbit, Anti-Cytochrome P450 4B1 antibody produced in rabbit, Anti-P450-HP antibody produced in rabbit

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À vous/Référence	Disponibilité	Prix
100 μL	Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.	881,00 $

A propos de cet article

UNSPSC Code:

12352203

NACRES:

NA.43

Human Protein Atlas Number:

HPA004331

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC

Citations:

881,00 $

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Propriétés

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies^® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunohistochemistry: 1:20-1:50

immunogen sequence

TGSLDKVVSWAHQFPYAHPLWFGQFIGFLNIYEPDYAKAVYSRGDPKAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGH

UniProt accession no.

P13584

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CYP4B1(1580)

Description

General description

CYP4B1 (cytochrome P450, family 4, subfamily B, polypeptide 1) is a member of extra-hepatic CYP450 family highly expressed in the lung. More specifically it is observed in the ciliated sub-mucosal gland ducts as well as in the surface epithelium.

Immunogen

Cytochrome P450 4B1 recombinant protein epitope signature tag (PrEST)

Application

Anti-CYP4B1 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project . Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

Biochem/physiol Actions

CYP4B1 (cytochrome P450, family 4, subfamily B, polypeptide 1) plays an important role in wound healing and inflammation in the ocular surface by increasing the production of the inflammatory 12-hydroxyeicosanoids in the corneal epithelium. It has high impact on the activation of environmental chemicals associated with breast cancer genesis. Various xenobiotics such as 2-aminofluorene, 2-naphthylamine and benzidine are metabolised by CYP4B1.

Features and Benefits

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
Protein array of 364 human recombinant protein fragments.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Other Notes

Corresponding Antigen APREST85168

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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1 of 1

Cet article	SAB4500603	HPA009128	HPA000525
Sigma-Aldrich HPA004331 Anti-CYP4B1 antibody produced in rabbit	Sigma-Aldrich SAB4500603 Anti-Cytochrome P450 4B1 antibody produced in rabbit	Sigma-Aldrich HPA009128 Anti-CYP2E1 antibody produced in rabbit	Sigma-Aldrich HPA000525 Anti-ADSL antibody produced in rabbit
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 100	Quality Level -	Quality Level 100	Quality Level 100
product line Prestige Antibodies^® Powered by Atlas Antibodies	product line -	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies
form buffered aqueous glycerol solution	form buffered aqueous solution	form buffered aqueous glycerol solution	form buffered aqueous glycerol solution

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c