Each package size available - 50 mg, 100 mg, 500 mg, 1 g, and 5 g - is packaged in a single HDPE bottle.
N8129
β-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate
≥97% (HPLC)
Synonym(s):
β-DPNH, β-NADH, DPNH, Diphosphopyridine nucleotide, reduced form, NADH
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| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Check Cart for Availability | $50.10 |
100 mg | Check Cart for Availability | $73.30 |
500 mg | Check Cart for Availability | $175.00 |
1 g | Estimated to ship onOctober 05, 2026fromMILWAUKEE | $215.00 |
5 g | Check Cart for Availability | $958.00 |
About This Item
Empirical Formula (Hill Notation):
C21H27N7Na2O14P2 · xH2O
CAS Number:
Molecular Weight:
709.40 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
210-123-3
MDL number:
Form:
powder
Assay:
≥97% (HPLC), ≥97% (spectrophotometric assay)
Solubility:
water: 712 g/L at 22.5 °C, 10 mM NaOH: soluble-100 mg/mL, clear to slightly hazy, faintly yellow to greenish-yellow
Biological source:
yeast
Color:
white to light yellow
biological source
yeast
Quality Segment
assay
≥97% (HPLC), ≥97% (spectrophotometric assay)
form
powder
mol wt
709.40 g/mol
color
white to light yellow
solubility
water: 712 g/L at 22.5 °C, 10 mM NaOH: soluble-100 mg/mL, clear to slightly hazy, faintly yellow to greenish-yellow
density
1.995 g/cm3 at 20 °C
storage temp.
−20°C
SMILES string
O.[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
InChI
1S/C21H29N7O14P2.2Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;;1H2/q;2*+1;/p-2/t10-,11-,13-,14-,15-,16-,20-,21-;;;/m1.../s1
InChI key
FWBNCIFELNNJCX-UHOVGGJYSA-L
Application
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.
Biochem/physiol Actions
NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, β-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). It participates in cell signaling events as well, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. The NAD+/NADH dependent sirtuins play key roles in stress responses during events involving energy metabolism, with implications in cancer biology, diabetes and neurodegenerative disease.
As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.
As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.
Packaging
Packaged by solid weight.
1 of 1
This Item | |||
|---|---|---|---|
| description ≥97% (HPLC) | description ≥95.0% (HPLC) | description Grade II, disodium salt | description ≥94% (HPLC) |
| assay ≥97% (spectrophotometric assay), ≥97% (HPLC) | assay ≥95.0% (HPLC) | assay 98% | assay ≥94% (spectrophotometric assay), ≥94% (HPLC) |
| solubility 10 mM NaOH: soluble-100 mg/mL, clear to slightly hazy, faintly yellow to greenish-yellow, water: 712 g/L at 22.5 °C | solubility - | solubility - | solubility 10 mM NaOH: soluble-100 mg/mL, clear to slightly hazy, slightly yellow to deep greenish-yellow |
| biological source yeast | biological source - | biological source - | biological source yeast |
| Quality Level 300 | Quality Level 200 | Quality Level - | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. - | storage temp. −20°C |
| form powder | form powder | form amorphous powder | form powder |
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Storage Class
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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