If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
P1851
PIPES
BioPerformance Certified, suitable for cell culture
Synonym(s):
1,4-Piperazinediethanesulfonic acid, Piperazine-1,4-bis(2-ethanesulfonic acid), Piperazine-N,N′-bis(2-ethanesulfonic acid)
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
25 g | Available to ship TODAYfromMILWAUKEE | $44.90 |
100 g | Available to ship TODAYfromMILWAUKEE | $141.00 |
500 g | Available to ship TODAYfromMILWAUKEE | $571.00 |
1 kg | Available to ship TODAYfromMILWAUKEE | $1,010.00 $757.50 |
About This Item
$44.90
Available to ship TODAYDetails
Quality Segment
grade
BioPerformance Certified, Molecular Biology
form
crystalline powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin and Total Aerobic Microbial Count, tested
useful pH range
6.1-7.5
pKa (25 °C)
6.8
mp
>300 °C (lit.)
solubility
1 M NaOH: 20 + 80 mL g, clear, colorless, soluble
application(s)
diagnostic assay manufacturing
foreign activity
DNAse, Exonuclease; NICKase, Endonuclease; RNAse; Protease, none detected
SMILES string
OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
InChI
1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
InChI key
IHPYMWDTONKSCO-UHFFFAOYSA-N
Application
- Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).
1 of 1
This Item | |||
|---|---|---|---|
| description BioPerformance Certified, suitable for cell culture | description ≥99% (titration) | description BioXtra, ≥99% (titration) | description BioXtra, Molecular Biology, ≥99.5% (T) |
| grade BioPerformance Certified, Molecular Biology | grade - | grade - | grade Molecular Biology |
| technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) - | technique(s) - |
| Quality Level 400 | Quality Level 400 | Quality Level 400 | Quality Level 100 |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) - |
| form crystalline powder | form crystalline powder | form powder | form powder |
| solubility 1 M NaOH: 20 + 80 mL g, clear, colorless, soluble | solubility 1 M NaOH: 20 + 80 mL g, clear, colorless | solubility 1 M NaOH: 0.5 M at 20 °C, clear, colorless | solubility 0.1 M NaOH: 0.1 M at 20 °C, clear, colorless |
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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How can I determine the shelf life / expiration / retest date of this product?
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Helpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
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Hi, I bought PIPES and HEPES powder for a buffer solution. Should I store those at room temperature or fridge (4C)? Thank you Andrea
1 answer-
In powder form, both the PIPES and HEPES may be stored tightly sealed at room temperature.
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