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Anti-α₁-Antitrypsin antibody produced in rabbit

Name: Anti-α<SUB>1</SUB>-Antitrypsin antibody produced in rabbit
Brand: SIGMA

IgG fraction of antiserum

Synonym(s):

Alpha 1 Antitrypsin Antibody, Alpha 1 Antitrypsin Antibody - Anti-α1-Antitrypsin antibody produced in rabbit, anti-A1AT

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.46

MDL number:

MFCD00162392

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IEP

Citations:

Pricing and availability is not currently available.

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Properties

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

mol wt

antigen ~50 kDa

species reactivity

human

packaging

vial of 2 mL lyophilized antiserum

technique(s)

immunoelectrophoresis: suitable, indirect ELISA: 1:30,000-1:60,000

UniProt accession no.

P01009

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... SERPINA1(5265)

Description

General description

α-1-antitrypsin belongs to the serpin family and is a strong serine protease inhibitor. Its pivotal role is to protect lower respiratory tract against proteolytic destruction by human leukocyte elastase. Mutation in AAT gene will reduce the serum concentration of α-1-antitrypsin and hence increase the risk of emphysema. Anti-α1-antitrypsin antibody (diluted 1:9000) can be used as a capture antibody for determination of transgene expressions levels. It can also be used in immunoelectrophoresis. Rabbit anti-α1-antitrypsin antibody reacts specifically with α1-antitrypsin of human.

Immunogen

Purified human α-1-antitrypsin

Application

Rabbit anti-α1-antitrypsin antibody can also be used in immunoelectrophoretic techniques.

Anti-α1-antitrypsin antibody (diluted 1: 1000) can be used in ELISA. It can also be used for probing immunoblots to identify A1AT. Additionally, it can be used in Ouchterlony double diffusion.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB4200198	HPA001292	HPA000927
$Anti-α1-Antitrypsin antibody produced in rabbit IgG fraction of antiserum$ Sigma-Aldrich A0409 Anti-α₁-Antitrypsin antibody produced in rabbit	Sigma-Aldrich SAB4200198 Anti-Alpha-1-Antitrypsin (AAT) antibody,Mouse monoclonal	Sigma-Aldrich HPA001292 Anti-SERPINA1 antibody produced in rabbit	Sigma-Aldrich HPA000927 Anti-SERPINA1 antibody produced in rabbit
description IgG fraction of antiserum	description clone 1C2, purified from hybridoma cell culture	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
biological source rabbit	biological source mouse	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 200	Quality Level -	Quality Level 100	Quality Level 100
antibody form IgG fraction of antiserum	antibody form purified from hybridoma cell culture	antibody form affinity isolated antibody	antibody form affinity isolated antibody
species reactivity human	species reactivity human	species reactivity human	species reactivity human
clone polyclonal	clone 1C2, monoclonal	clone polyclonal	clone polyclonal

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Storage Class

10 - Combustible liquids

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WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Key Documents

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Anti-α₁-Antitrypsin antibody produced in rabbit

IgG fraction of antiserum

Select a Size

About This Item

biological source

Quality Segment

conjugate

antibody form

antibody product type

clone

mol wt

species reactivity

packaging

technique(s)

UniProt accession no.

storage temp.

target post-translational modification

Gene Information

General description

Immunogen

Application

Physical form

Disclaimer

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Storage Class

wgk

flash_point_f

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Documentation

Certificates of Analysis (COA)

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