A0781
Aphidicolin from Nigrospora sphaerica
≥98% (HPLC), DNA polymerase inhibitor, powder
Synonym(s):
APC
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 mg | Check Cart for Availability | $146.00 |
5 mg | Available to ship TODAYfromMILWAUKEE | $641.00 |
10 mg | Available to ship TODAYfromMILWAUKEE | $1,190.00 |
About This Item
Product Name
Aphidicolin from Nigrospora sphaerica, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]27/D +12°, c = 1 in methanol(lit.)
color
white
mp
227-233 °C (lit.)
solubility
ethanol: 1 mg/mL (stable at least a week at 4°C.), DMSO: 10 mg/mL (stable at least six weeks at −20°C.), methanol: 10 mg/mL, H2O: insoluble
antibiotic activity spectrum
neoplastics, viruses
mode of action
DNA synthesis | interferes
storage temp.
2-8°C
SMILES string
[H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4
InChI
1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
InChI key
NOFOAYPPHIUXJR-APNQCZIXSA-N
Gene Information
human ... POLA1(5422), POLD1(5424), POLG(5428)
Biochem/physiol Actions
Features and Benefits
Disclaimer
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC), powder | description Aphidicolin, CAS 38966-21-1, is a cell-permeable antibiotic that acts as a cell synchronization agent. Blocks the cell cycle at early S-phase. | description analytical standard | description Ready Made Solution, from Nigrospora sphaerica |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay - |
| form powder | form solid | form - | form ready-to-use solution, liquid |
| Quality Level 300 | Quality Level 100 | Quality Level 100 | Quality Level 200 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| solubility H2O: insoluble, ethanol: 1 mg/mL (stable at least a week at 4°C.), DMSO: 10 mg/mL (stable at least six weeks at −20°C.), methanol: 10 mg/mL | solubility ethanol: soluble, methanol: soluble, DMSO: 50 mg/mL | solubility - | solubility H2O: miscible (completely) |
| color white | color white | color - | color clear colorless |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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