Skip to Content
MilliporeSigma

Skip To

A1755

Aminophylline

≥98%, powder

Synonym(s):

(Theophylline)2 · Ethylenediamine, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, cmpd. with 1,2-ethanediamine (2:1), Theophylline hemi(ethylenediamine) complex

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
25 g

Available to ship TODAYfromMILWAUKEE

$74.40
100 g

Available to ship TODAYfromMILWAUKEE

$131.00

About This Item

Empirical Formula (Hill Notation):
C7H8N4O2 · 0.5C2H8N2
CAS Number:
Molecular Weight:
210.21
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
206-264-5
MDL number:
eCl@ss:
32119108
Assay:
≥98%
Form:
powder

$74.40


Available to ship TODAYDetails


​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

assay

≥98%

form

powder

color

white to off-white

solubility

H2O: 50 mg/mL (solutions should be freshly prepared.), alcohol: insoluble

storage temp.

−20°C

SMILES string

NCCN.CN1C(=O)N(C)c2nc[nH]c2C1=O.CN3C(=O)N(C)c4nc[nH]c4C3=O

InChI

1S/2C7H8N4O2.C2H8N2/c2*1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;3-1-2-4/h2*3H,1-2H3,(H,8,9);1-4H2

InChI key

FQPFAHBPWDRTLU-UHFFFAOYSA-N

Application

Aminophylline has been used:
  • as a positive control in the selective inhibitor of nuclear export, KPT-350 zebrafish dosing experiments
  • as a positive control for the determination of the spasmolytic activity of C. aeruginosa extracts
  • as a phosphodiesterase (PDE) inhibitor in inhibitor studies to quantify its potency to inhibit PDE4A1A and PDE3A enzyme in an assay

Biochem/physiol Actions

Non-selective phosphodiesterase (PDE) inhibitor. Antiepileptic drug
Aminophylline is a methylxanthine compound containing theophylline andethylenediamine in a ratio of 2:1. It acts as a bronchodilator and is used to treat chronic lung diseases like asthma, bronchitis, or emphysema.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
P3800000SML1766C6144
description

≥98%, powder

description

European Pharmacopoeia (EP) Reference Standard

description

≥98% (HPLC)

description

from Anacystis nidulans algae

form

powder

form

-

form

powder

form

powder

assay

≥98%

assay

-

assay

≥98% (HPLC)

assay

-

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

alcohol: insoluble, H2O: 50 mg/mL (solutions should be freshly prepared.)

solubility

-

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

diethyl ether: 0.1 mg/10 mL

color

white to off-white

color

-

color

white to light brown

color

blue to very dark blue


Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Codes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters