Key Documents

View All Documentation

Activin A human

Name: Activin A human
Brand: SIGMA
Price: 465 CAD

≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, lyophilized powder, suitable for cell culture

Synonym(s):

Activin A Protein, Growth Factor, Human Growth Factor

Select a Size

Change View

Pack Size	SKU	Availability	Price
10 μg		Please contact Customer Service for Availability	$465.00

About This Item

UNSPSC Code:

12352202

NACRES:

NA.32

EC Number:

201-069-1

MDL number:

MFCD02685750

Biological source:

human

Recombinant:

expressed in baculovirus infected insect cells

Assay:

≥95% (SDS-PAGE)

Form:

lyophilized powder

Mol wt:

dimer 26 kDa (containing 116 amino acid residues βA subunits)

Impurities:

endotoxin, tested

$465.00

Please contact Customer Service for Availability

Request a Bulk Order

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Activin A human, ≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, lyophilized powder, suitable for cell culture

biological source

human

Quality Level

200

recombinant

expressed in baculovirus infected insect cells

assay

≥95% (SDS-PAGE)

form

lyophilized powder

potency

1-10 ng/mL ED₅₀

mol wt

dimer 26 kDa (containing 116 amino acid residues βA subunits)

packaging

pkg of 10 μg, pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P08476

storage temp.

−20°C

Gene Information

human ... INHBA(3624)

Description

General description

Activin A gene with two exons is mapped to human chromosome 2q35. Activin A also known as inhibin α-subunit belongs to the TGF-β (transforming growth factor-β) superfamily of proteins and its expression is exclusive to gonads, placenta and adrenal cortex.

Application

Activin A human has been used as a constituent of modified barth′s saline used in in vitro induction of pronephros.[1] It has also been used as a constituent of Roswell Park memorial institute (RPMI) media to induce pancreatic differentiation of multipotent dermal fibroblasts in vitro.

Biochem/physiol Actions

Activins play a vital role in the regulation of hormonogenesis, cellular homeostasis and differentiation programs.[2] Elevated expression of activin A and B leads to the loss of muscle mass. Both activin A and B have a potential to act as a serum markers of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME).

Physical form

Lyophilized from 0.2 μm filtered solution in 10 mM sodium citrate, pH 3.0.

Analysis Note

The biological activity is determined by its ability to inhibit the proliferation of mouse MPC-11 cells.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	A4362	H8541	SRP3003
Sigma-Aldrich A4941 Activin A human	Sigma-Aldrich A4362 Activin A active human	Sigma-Aldrich H8541 Transforming Growth Factor-β1 human	Sigma-Aldrich SRP3003 Activin A human
technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
biological source human	biological source human	biological source human	biological source human
recombinant expressed in baculovirus infected insect cells	recombinant expressed in Nicotiana	recombinant expressed in HEK 293 cells	recombinant expressed in E. coli
assay ≥95% (SDS-PAGE)	assay >97% (SDS-PAGE)	assay ≥95% (SDS-PAGE)	assay ≥97% (HPLC), ≥97% (SDS-PAGE)
Quality Level 200	Quality Level 100	Quality Level 300	Quality Level -
form lyophilized powder	form lyophilized	form lyophilized powder	form lyophilized

Still not finding the right product?

Explore all of our products under Activin A human

pictograms

GHS07

signalword

Warning

hcodes

H319,H335

pcodes

P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Naive Pluripotent Stem Cell Culture in Serum-Free Media

Naive pluripotent stem cells cultured in vitro using specialized media and inhibitors mimic "ground-state" cells from blastocysts.

Global Trade Item Number

SKU	GTIN
A4941-5UG	04061833375280
A4941-10UG	04061833375273

Questions

Reviews

No rating value