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A4941

激活素 A 人

≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, lyophilized powder, suitable for cell culture

同義詞:

人生长因子, 激活素A蛋白, 生长因子

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關於此項目

UNSPSC Code:
12352202
NACRES:
NA.32
EC Number:
201-069-1
MDL number:
Biological source:
human
Recombinant:
expressed in baculovirus infected insect cells
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
dimer 26 kDa (containing 116 amino acid residues βA subunits)
Impurities:
endotoxin, tested
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產品名稱

激活素 A 人, ≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, lyophilized powder, suitable for cell culture

biological source

human

Quality Segment

recombinant

expressed in baculovirus infected insect cells

assay

≥95% (SDS-PAGE)

form

lyophilized powder

potency

1-10 ng/mL ED50

mol wt

dimer 26 kDa (containing 116 amino acid residues βA subunits)

packaging

pkg of 10 μg, pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... INHBA(3624)

General description

带有两个外显子的激活素A基因位于人染色体2q35上。激活素A也称为抑制素α-亚基,属于蛋白质的TGF-β(转化生长因子β)超家族,其表达仅限于性腺、胎盘和肾上腺皮质。

Application

人激活素A已被用作 modified barth′s saline 的成分,用于体外诱导前肾。[1]它还被用作罗斯威尔公园纪念研究所(RPMI)培养基的成分,用于在体外诱导多能真皮成纤维细胞的胰腺分化。

Biochem/physiol Actions

激活素在激素生成、细胞稳态和分化程序的调节中起着至关重要的作用。[2]激活素A和B的表达升高会导致肌肉质量下降。激活素A和B都有望用作慢性疲劳综合征/肌痛性脑脊髓炎(CFS / ME)的血清标志物。

Physical form

0.2μ 冻干10 mM 柠檬酸钠 (pH 3.0) 滤过溶液。

Analysis Note

其生物活性由其抑制小鼠 MPC-11 细胞增殖的能力决定。

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本產品
A4362T2815H8916
biological source

human

biological source

human

biological source

human

biological source

human

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

assay

≥95% (SDS-PAGE)

assay

>97% (SDS-PAGE)

assay

≥97% (electrophoresis)

assay

≥95% (SDS-PAGE)

recombinant

expressed in baculovirus infected insect cells

recombinant

expressed in Nicotiana

recombinant

expressed in NSO cells

recombinant

expressed in HEK 293 cells

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

form

lyophilized powder

form

lyophilized

form

powder

form

lyophilized powder


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存儲類別/等級

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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