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Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse

Name: Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse
Brand: SIGMA
Price: 552 USD
Availability: InStock

ascites fluid, clone C3

Synonym(s):

Afp Antibody, Afp Antibody - Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse, Alpha Fetoprotein Antibody

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Size/SKU	Availability	Price
100 μL	Estimated to ship TODAYfromMILWAUKEE	$552.00
0.2 mL	Estimated to ship TODAYfromMILWAUKEE	$763.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.46

MDL number:

MFCD00162111

Conjugate:

unconjugated

Clone:

C3, monoclonal

Application:

DB, ELISA (i), IHC (p)

Citations:

$552.00

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Properties

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

C3, monoclonal

contains

15 mM sodium azide

species reactivity

pig, canine, human

should not react with

mouse, cat, rat, bovine

technique(s)

dot blot: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500 using human fetal liver, indirect ELISA: suitable

isotype

IgG2a

UniProt accession no.

P02771

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... AFP(174)

Description

General description

α-Fetoprotein (AFP) is a one of the main glycoprotein present in the fetal liver, gastrointestinal tract, and yolk sac. AFP levels in amniotic fluid have been used as biomarkers for anencephaly and spina bifida.

AFP is a plasma protein found highly expressed in the human fetus where it functions to block the transport of estradiol across the placenta.

Monoclonal Anti-α-Fetoprotein (AFP) (mouse IgG2a isotype) is derived from the C3 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified human α-fetoprotein.

Immunogen

human α-fetoprotein

Application

Mouse Monoclonal Anti-α-Fetoprotein has been used for immunocytochemistry. The product can also be used for dot blot and indirect ELISA.

Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse has been used in:

enzyme-linked immunosorbent assay (ELISA)
dot blot
immunocytochemistry
immunofluorescence
immunocytochemistry

Biochem/physiol Actions

Increased concentrations of α-fetoprotein (AFP) in serum are less common in patients with malignancies of the gastrointestinal tract and of other organ systems with massive hepatic metastases. Hence, AFP determination is useful for the diagnosis of certain germ line tumors that contain yolk sac structures (testicular and ovarian tumors), hepatocellular carcinoma (hepatoma), and some malignant tumors of the gastrointestinal tract. AFP serves as an important marker for certain genetic and embryonic defects. Routine screening of pregnancies with a risk of neural tube defects (spina bifida, anencephaly, and Down′s syndrome) may be facilitated by the monitoring of AFP levels.

Physical form

The product is provided as ascites fluid with 0.1% sodium azide as a preservative.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	WH0000174M1	MABX5511	SAB3500533
Sigma-Aldrich A8452 Monoclonal Anti-α-Fetoprotein (AFP) antibody produced in mouse	Sigma-Aldrich WH0000174M1 Monoclonal Anti-AFP antibody produced in mouse	Sigma-Aldrich MABX5511 Anti-AFP (1mg) KC	Sigma-Aldrich SAB3500533 Anti-AFP antibody produced in rabbit
description ascites fluid, clone C3	description clone 1G7, purified immunoglobulin, buffered aqueous solution	description Chemicon^®, from mouse	description affinity isolated antibody, buffered aqueous solution
species reactivity pig, canine, human	species reactivity human	species reactivity human	species reactivity human, mouse, rat
conjugate unconjugated	conjugate unconjugated	conjugate -	conjugate unconjugated
biological source mouse	biological source mouse	biological source mouse	biological source rabbit
Gene Information human ... AFP(174)	Gene Information human ... AFP(174)	Gene Information human ... AFP(174)	Gene Information human ... AFP(174)
clone C3, monoclonal	clone 1G7, monoclonal	clone monoclonal	clone polyclonal
antibody form ascites fluid	antibody form purified immunoglobulin	antibody form purified antibody	antibody form affinity isolated antibody

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Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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